3-Fluoro-4-hydroxyphenylacetic acid

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Names

[ CAS No. ]:
458-09-3

[ Name ]:
3-Fluoro-4-hydroxyphenylacetic acid

[Synonym ]:
2-(3-fluoro-4-hydroxyphenyl)acetic acid
3-Fluoro-4-hydroxyphenylacetic acid
EINECS 207-275-8
MFCD00004348

Chemical & Physical Properties

[ Density]:
1.423 g/cm3

[ Boiling Point ]:
320.3ºC at 760 mmHg

[ Melting Point ]:
132-134 °C(lit.)

[ Molecular Formula ]:
C8H7FO3

[ Molecular Weight ]:
170.13800

[ Flash Point ]:
147.5ºC

[ Exact Mass ]:
170.03800

[ PSA ]:
57.53000

[ LogP ]:
1.15840

[ Vapour Pressure ]:
0.000133mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (3-Fluoro-4-methoxyphenyl)acetic acid
  • 3-Fluoro-4-methoxybenzyl cyanide
  • 3-Fluoro-4-hydroxymandelic acid
  • 2-Fluoroanisole
  • 3'-Fluoro-4'-hydroxyacetophenone
  • 3-Fluoro-4-methoxybenzylchloride
  • 2-Fluorophenol
  • Ethyl 3-fluoro-4-methoxybenzoylformate
  • 2-(3-fluoro-4-methoxyphenyl)-2-oxoacetic acid
  • Pyridine chlorhydrate

DownStream

  • methyl 2-(4-cyano-3-fluorophenyl)acetate
  • Benzeneethanol,3-fluoro-4-hydroxy-

Articles

An in vivo microdialysis study of striatal 6-[18F]fluoro-L-m-tyrosine metabolism.

Neurochem. Res. 23(4) , 513-7, (1998)

In vivo brain microdialysis was used to monitor 6-[18F]fluoro-L-m-tyrosine (FMT) uptake and metabolism in the striatum of conscious freely moving rats for 3 hours after FMT injection (25 mg/kg, i.v.)....


More Articles

Related Compounds

  • 3-Fluoro-4-methoxybenzoic acid
  • 3-Fluoro-4-hydroxybenzoic acid
  • 3-Fluoro-4-nitrobenzenesulfonic acid
  • 3-Fluoro-4-morpholinophenylboronic Acid
  • 3-Fluoro-4-hydroxymandelic acid
  • 3-Fluoro-4-nitrobenzoic acid
  • 7-Bromo-6-[diethoxyphosphoryl(difluoro)methyl]naphthalene-2-carbonitrile
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 5-(2-Bromophenyl)-3-methyloxazolidin-2-one
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 5-Chloro-2-fluoro-3-methylbenzoyl chloride
  • Tert-butyl 2-(aminomethyl)pentanoate hydrochloride
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide