(2-Chloroethyl)dimethylamine hydrochloride
Suppliers
Names
[ CAS No. ]:
4584-46-7
[ Name ]:
(2-Chloroethyl)dimethylamine hydrochloride
[Synonym ]:
N-(2-chloroethyl)-N,N-dimethylamine hydrochloride
DMC-HCl
MFCD00012516
(β-Chloroethyl)dimethylamine hydrochloride
2-(dimethylamino)-ethylchloride hydrochloride
N,N-Dimethyl-2-ChloroethylamineHCl
2-(N,N-dimethylamino)ethylchloride hydrochloride
DIMETHYLAMINOETHYLCHLORIDE HCL
DMC
2-Chloro-N,N-dimethylethanamine hydrochloride (1:1)
Ethanamine, 2-chloro-N,N-dimethyl-, hydrochloride (1:1)
2-Chloro-N,N-dimethylethylamine Hydrochloride
Dimethyl cyclosiloxane
2-Dimethylaminoethyl chloride hydrochloride
2-dimethylamino-1-chloro-ethane hydrochloride
(2-Chloroethyl)dimethylamine hydrochloride
N,N-DimethylaminoChloroethaneHCl
β-Dimethylaminoethyl chloride hydrochloride
2-chloro-N,N-dimethylaminoethane hydrochloride
2-Dimethylaminoethyl
N,N-dimethylamino-2-chloroethane hydrochloride
N-(2-Chloroethyl) Dimethyl HCl
EINECS 224-970-1
1-chloro-2-(N,N-dimethylamino)ethane hydrochloride
N,N-DIMETHYL(2-CHLOROETHYL)-AMINE
2-Chloro-N,N-dimethylethanamine hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
57.8ºC at 760 mmHg
[ Melting Point ]:
201-204 °C(lit.)
[ Molecular Formula ]:
C4H11Cl2N
[ Molecular Weight ]:
144.043
[ Flash Point ]:
21.6ºC
[ Exact Mass ]:
143.026855
[ PSA ]:
3.24000
[ LogP ]:
1.58880
[ Water Solubility ]:
2000 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KQ9020000
- CHEMICAL NAME :
- Ethylamine, 2-chloro-N,N-dimethyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 4584-46-7
- LAST UPDATED :
- 199804
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- C4-H10-Cl-N.Cl-H
- MOLECULAR WEIGHT :
- 144.06
- WISWESSER LINE NOTATION :
- G2N1&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 238 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 290 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes Blood - hemorrhage Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 117 mg/kg/7D-I
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Liver - hepatitis (hepatocellular necrosis), diffuse Nutritional and Gross Metabolic - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 720 mg/kg/8W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - rat Cells - not otherwise specified
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1697,1987
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H311-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338-P312
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+:Verytoxic;N:Dangerous for the environment;
[ Risk Phrases ]:
R22;R24;R26;R36/37/38;R51/53;R68
[ Safety Phrases ]:
S26-S36/37-S45-S61-S36/37/39-S28A
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
KQ9020000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
29211980
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921199090
[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%