1-Bromo-3,5-difluorobenzene

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Names

[ CAS No. ]:
461-96-1

[ Name ]:
1-Bromo-3,5-difluorobenzene

[Synonym ]:
3,5-difluoro-1-bromobenzene
4-bromo-2,6-difluorobenzene
EINECS 416-710-2
1-Bromo-3,5-difluoro benzene
1-Bromo-3,5-difluorobenzene
5-difluorobenzene
1-Bromo-3,5-difluoro
5-bromo-1,3-difluorobenzene
MFCD00010305
3,5-Difluorobromobenzene
1-bromo-3,5-difluoro-benzene
1-bromo-3,5-difluorobenene
FR CF EE
Benzene, 1-bromo-3,5-difluoro-
1-Brom-3,5-difluorbenzol

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
140.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-27 °C

[ Molecular Formula ]:
C₆H₃BrF₂

[ Molecular Weight ]:
192.989

[ Flash Point ]:
44.4±0.0 °C

[ Exact Mass ]:
191.938614

[ LogP ]:
3.11

[ Vapour Pressure ]:
7.8±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.507

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
0.238 g/L (20 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H302-H315-H317-H373-H410

[ Precautionary Statements ]:
P273-P280-P501

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R10;R22;R38;R43;R48/22;R50/53

[ Safety Phrases ]:
S24-S36/37-S60-S61

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
2

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2903399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Hypophosphorous acid
2-bromo-4,6-difluoroaniline hydrobromide
1,3-Dibromo-5-fluorobenzene
2-Bromo-4,6-difluoroaniline
Cuprous oxide
2,4-Difluoroaniline
1,3-Difluorobenzene
(2,6-difluorophenyl)-triethylsilane
(3-bromo-2,6-difluorophenyl)-triethylsilane

DownStream

1,3-Difluorobenzene
Chlorobenzene
Benzonitrile
3,5-Difluorobenzoic acid
3,5-Difluorobenzaldehyde
[(3,5-Difluorophenyl)ethynyl](trimethyl)silane
3-Fluoro-5-bromophenol
3-(3,5-DIFLUORO-PHENYL)-PROPIONALDEHYDE
Dibenzyl ether
3-(3,5-difluorophenyl)propanoic acid

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Regioselective ortho-lithiation of chloro and bromo substituted fluoroarenes.

Tetrahedron Lett. 37(36) , 6551-6554, (1996)