(+)-Ophiobolin A
Suppliers
Names
[ CAS No. ]:
4611-05-6
[ Name ]:
(+)-Ophiobolin A
[Synonym ]:
COCHLIOBOLIN A
(18R)-3-Hydroxy-5-oxo-14,18-epoxyophiobola-7,19-diene-25-al
18-epoxy-3-hydroxy-5-oxo-19-dien-25-a(18r)-ophiobola-14
Ophiobolin A
cochliobolin
ophiobolin
Ophiobolin,Helminthosporium sp.
orphiobolin A
(7E,18R)-3-Hydroxy-5-oxo-14,18-epoxyophiobola-7,19-dien-25-al
Spiro[dicyclopenta[a,d]cyclooctene-3(2H),2'(3'H)-furan]-6-carboxaldehyde, 1,3a,4,4',5',6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3',9,10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxo-, (3S,3'S,3aR,5E,5'R,6aS,9R,9aS,10aR)-
(18R)-14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
539.4±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C25H36O4
[ Molecular Weight ]:
400.551
[ Flash Point ]:
177.8±23.6 °C
[ Exact Mass ]:
400.261353
[ PSA ]:
63.60000
[ LogP ]:
3.75
[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C
[ Index of Refraction ]:
1.554
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RL1576000
- CHEMICAL NAME :
- Ophiobola-7,19-dien-25-al, 14,18-epoxy-3-hydroxy-5-oxo-, (18R)-
- CAS REGISTRY NUMBER :
- 4611-05-6
- LAST UPDATED :
- 198211
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C25-H36-O4
- MOLECULAR WEIGHT :
- 400.61
- WISWESSER LINE NOTATION :
- L C585 FV LX HUTJ A1 DQ D1 HVH L-& BT5OXTJ C1 E1UY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 238 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,143,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,143,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 73 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,143,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 12 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,143,1981
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H312 + H332
[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P261-P280
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22
[ Safety Phrases ]:
S36
[ RIDADR ]:
UN 2811 6.1/PG 3
[ RTECS ]:
RL1576000