Glycine,N-(aminocarbonyl)-

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Names

[ CAS No. ]:
462-60-2

[ Name ]:
Glycine,N-(aminocarbonyl)-

[Synonym ]:
N-Carboxymethylurea
HYDANTOIC ACID
N-Carbamoylglycine
EINECS 207-328-5
2-(carbamoylamino)acetic acid
MFCD00047876

Chemical & Physical Properties

[ Density]:
1.434g/cm3

[ Boiling Point ]:
174 °C7 mm Hg(lit.)

[ Melting Point ]:
37-41 °C(lit.)

[ Molecular Formula ]:
C3H6N2O3

[ Molecular Weight ]:
118.09100

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
118.03800

[ PSA ]:
92.42000

[ Vapour Pressure ]:
4.18E-05mmHg at 25°C

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MB7660000
CHEMICAL NAME :
Glycine, N-(aminocarbonyl)-
CAS REGISTRY NUMBER :
462-60-2
BEILSTEIN REFERENCE NO. :
1812022
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C3-H6-N2-O3
MOLECULAR WEIGHT :
118.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 24(4),32,1990

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ WGK Germany ]:
3

[ RTECS ]:
MB7660000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Glycine
  • (S)-(-)-4-Isobutyloxazolidine-2,5-Dione
  • 4-Benzyloxazolidine-2,5-dione
  • Potassium cyanate
  • L-alanine
  • L-Valine
  • 4-(1-Methylpropyl)oxazolidine-2,5-dione
  • L-Isoleucine
  • L-Phenylalanine
  • N-Nitrocarbamide

DownStream

  • methyl (4,6-dimethyl-2-oxo-3a,6a-diphenyl-5-thioxooctahydroimidazo[4,5-d]imidazol-1-yl)acetate
  • 4,5-dimethoxy-1,3-dimethyl-4,5-diphenyltetrahydroimidazole-2-thione
  • N,N'-Dimethylthiourea
  • Benzil
  • Imidazolidine-2,4-dione
  • (4,6-dimethyl-2-oxo-3a,6a-diphenyl-5-thioxooctahydroimidazo[4,5-d]imidazol-1-yl)acetic acid
  • Glycine, N-[(phenylamino)carbonyl]-
  • 2,5-Oxazolidinedione
  • Glycine,N-(aminocarbonyl)-, ethyl ester

Related Compounds

  • Glycine,N-(aminocarbonyl)-N-phenyl
  • Glycine,N-(aminocarbonyl)-, ethyl ester
  • Glycine, N-(aminocarbonyl)-, 1-methylethyl ester (9CI)
  • 2-[carbamoyl(nitroso)amino]acetic acid
  • Glycine, N-(1-oxo-2-((2-thienylcarbonyl)thio)propyl)-, 2-(butoxycarbon yl)phenyl ester
  • Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-methylhydrazide (9CI)
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • 2-(3-Fluorophenyl)oxan-4-amine