Cadaverine

Suppliers

Names

[ CAS No. ]:
462-94-2

[ Name ]:
Cadaverine

[Synonym ]:
1,5-Pentamethylenediamine
EINECS 207-329-0
Pentamethylenediamine
MFCD00008239
1,5-Pentanediamine
Pentane-1,5-diamine
1,5-Diaminopentane
Z5Z

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
179.0±8.0 °C at 760 mmHg

[ Melting Point ]:
9 °C

[ Molecular Formula ]:
C5H14N2

[ Molecular Weight ]:
102.178

[ Flash Point ]:
76.5±24.8 °C

[ Exact Mass ]:
102.115700

[ PSA ]:
52.04000

[ LogP ]:
-0.49

[ Vapour Pressure ]:
1.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.458

[ Stability ]:
Stable. Incompatible with acid chlorides, acids, acid anhydrides, strong oxidizing agents, carbon dioxide.

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SA0200000
CHEMICAL NAME :
1,5-Pentanediamine
CAS REGISTRY NUMBER :
462-94-2
BEILSTEIN REFERENCE NO. :
1697256
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C5-H14-N2
MOLECULAR WEIGHT :
102.21
WISWESSER LINE NOTATION :
Z5Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Rectal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
200 mmol/L
REFERENCE :
IJRBA3 International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. (Taylor & Francis Inc., 242 Cherry St., Philadelphia, PA 19106) V.1- 1959- Volume(issue)/page/year: 9,185,1965

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Supplemental HS ]:
Repeated exposure may cause skin dryness or cracking.

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S25

[ RIDADR ]:
UN 2735 8/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
SA0200000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2921290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • L-(+)-Lysine monohydrochloride
  • 1,5-Pentanediol
  • L-Lysine
  • Di-trifluoracetyl-diaminopentan-(1,5)
  • DL-Lysine
  • Glutaronitrile
  • Pentanenitrile, 5-amino-
  • cadaverine dihydrochloride
  • 1,5-Pentanediamine,N1,N5-bis(phenylmethylene)-

DownStream

  • 1-(N-methyl)-1,5-pentanediamine
  • N,N'-dimethylpentane-1,5-diamine
  • N1,N1-DIMETHYLPENTANE-1,5-DIAMINE
  • 9-azabicyclo[3.3.1]nonan-3-one
  • 1-(2-Piperidinyl)acetone
  • N-Boc-1,5-diaminopentane
  • N,N'-di-(tert-butoxycarbonyl)-1,5-diaminopentane
  • N-CARBOBENZOXY-1,5-DIAMINOPENTANE HYDROCHLORIDE
  • 2-N-(5-AMINOPENTYL)-AMINO-5-BROMOPYRIDINE
  • N-(5-aminopentyl)-4-[[4-(dimethylamino)phenyl]diazenyl]benzamide

Customs

[ HS Code ]: 2921290000

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

In vitro inhibition of lysine decarboxylase activity by organophosphate esters.

Biochem. Pharmacol. 92(3) , 506-16, (2014)

Organophosphate esters (OPEs), a major group of organophosphorus flame retardants, are regarded as emerging environmental contaminants of health concern. Amino acid decarboxylases catalyze the convers...

Mechanistic studies on the flavin-dependent N⁶-lysine monooxygenase MbsG reveal an unusual control for catalysis.

Arch. Biochem. Biophys. 550-551 , 58-66, (2014)

The mechanism of Mycobacterium smegmatis G (MbsG), a flavin-dependent l-lysine monooxygenase, was investigated under steady-state and rapid reaction conditions using primary and solvent kinetic isotop...

Optimization of Direct Lysine Decarboxylase Biotransformation for Cadaverine Production with Whole-Cell Biocatalysts at High Lysine Concentration.

J. Microbiol. Biotechnol. 25 , 1108-13, (2015)

Cadaverine (1,5-diaminopentane) is an important industrial chemical with a wide range of applications. Although there have been many efforts to produce cadaverine through fermentation, there are not m...


More Articles

Related Compounds

  • N-Boc-cadaverine
  • Biotincadaverine
  • N-Boc cadaverine
  • Biotincadaverine
  • Biotincadaverine
  • dansyl cadaverine
  • 7-methoxy-2-methylisoquinolin-1(2H)-one
  • 4-(N,N-diisobutylsulfamoyl)-N-(5-propyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)benzamide hydrochloride
  • Methyl 4-((5-propyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbamoyl)benzoate hydrochloride
  • 4-((3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-N-(5-propyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)benzamide hydrochloride
  • N-(5-benzyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)-2-(4-fluorophenyl)acetamide hydrochloride
  • 1-((Benzyloxy)methyl)-4,5-dibromo-2-(methylthio)-1H-imidazole
  • 3-(3,5-dimethoxybenzyl)-5-methoxy-1,6-dimethylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
  • 2-(6-ethyl-5-methoxy-1-methyl-2,4-dioxo-1,2-dihydropyrido[2,3-d]pyrimidin-3(4H)-yl)-N-(2-fluorophenyl)acetamide
  • Azafluorene
  • 2-(5-methoxy-1-methyl-2,4-dioxo-1,2-dihydropyrido[2,3-d]pyrimidin-3(4H)-yl)-N-(4-methoxyphenyl)acetamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.