7-Azaindole-3-carboxaldehyde

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Names

[ CAS No. ]:
4649-09-6

[ Name ]:
7-Azaindole-3-carboxaldehyde

[Synonym ]:
3-Formyl-1H-pyrrolo[2,3-b]pyridine
1H-pyrrolo[2,3-B]pyridine-3-carbaldehyde
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde
7-Azaindole-3-Carboxaldehyde
1H-Pyrrolo[2,3-b]pyridin-3-carbaldehyd

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
361.1±22.0 °C at 760 mmHg

[ Melting Point ]:
216-220ºC

[ Molecular Formula ]:
C8H6N2O

[ Molecular Weight ]:
146.146

[ Flash Point ]:
176.0±28.8 °C

[ Exact Mass ]:
146.048019

[ PSA ]:
45.75000

[ LogP ]:
1.21

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.747

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H317-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 7-Azaindole
  • N,N-Dimethylformamide
  • acetic acid
  • Aminoform
  • Dichloromethyl methyl ether
  • 3-Bromo-7-azaindole
  • 1H-Pyrrolo[2,3-b]pyridin-3-amin
  • SodiuM bicarbonate
  • 3-(DiMethylaMinoMethyl)-7-azaindole

DownStream

  • 3-ethenyl-1H-pyrrolo[2,3-b]pyridine
  • 4-bromo-2,5-dimethoxybenzene-1-sulfonyl chloride
  • 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 1-(phenylsulfonyl)-, ethyl ester
  • METHYL 1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE
  • 1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID
  • 1-(1H-Pyrrolo[2,3-b]pyridin-3-yl)ethanone
  • 3-(1-PIPERAZINYLMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE
  • 1H-Pyrrolo[2,3-B]Pyridin-3-Ylmethanol
  • tert-butyl 3-formyl-1H-pyrrolo[2,3-b]pyridine-1-carboxylate
  • TERT-BUTYL 3-(HYDROXYMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE-1-CARBOXYLATE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and antifungal activity of novel streptochlorin analogues.

Eur. J. Med. Chem. 92 , 776-83, (2015)

Streptochlorin, first isolated as a new antibiotic in 1988 from the lipophilic extracts of the mycelium of a Streptomyces sp, is an indole natural products with a variety of biological activities. Bas...

Synthesis and evaluation of fluorine-substituted 1H-pyrrolo[2,3-b]pyridine derivatives for dopamine D4 receptor imaging.

Bioorg. Med. Chem. 12 , 5505, (2004)

Seven fluorine-substituted 1H-pyrrolo[2,3-b]pyridine derivatives were synthesized based on a lead ligand, 3-[[4-(4-iodophenyl)piperazin-1-yl]-methyl]-1H-pyrrolo[2,3-b]pyridine (L-750,667) and evaluate...

J. Am. Chem. Soc. 77 , 457, (1995)


More Articles

Related Compounds

  • 7-azaindole-3-carboxaldehyde oxime
  • 5-iodo-7-azaindole-3-carboxaldehyde
  • 5-Fluoro-7-azaindole-3-carboxaldehyde
  • 6-Fluoro-7-azaindole-3-carboxaldehyde
  • 4-(Trifluoromethyl)-7-azaindole-3-carboxaldehyde
  • 5-(Trifluoromethyl)-7-azaindole-3-carboxaldehyde