Di(1-aziridinyl)methylphosphine oxide

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Names

[ CAS No. ]:
465-60-1

[ Name ]:
Di(1-aziridinyl)methylphosphine oxide

[Synonym ]:
HC 8106
Bis(1-aziridinyl)methylphosphine oxide
Phosphine oxide,bis(1-aziridinyl)methyl
Di(1-aziridinyl)methylphosphine oxide
Methyl(aziridinyl)phosphine oxide
Aziridine,1,1'-(methylphosphinylidene)bis

Chemical & Physical Properties

[ Density]:
1.29g/cm3

[ Boiling Point ]:
211.6ºC at 760 mmHg

[ Molecular Formula ]:
C5H11N2OP

[ Molecular Weight ]:
146.12700

[ Flash Point ]:
81.8ºC

[ Exact Mass ]:
146.06100

[ PSA ]:
32.90000

[ LogP ]:
0.31630

[ Vapour Pressure ]:
0.181mmHg at 25°C

[ Index of Refraction ]:
1.541

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SY9450000
CHEMICAL NAME :
Phosphine oxide, bis(1-aziridinyl)methyl-
CAS REGISTRY NUMBER :
465-60-1
LAST UPDATED :
198712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H11-N2-O-P
MOLECULAR WEIGHT :
146.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
44 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 28,70,1965

Related Compounds

  • Butylaminobis(1-aziridinyl)phosphine oxide
  • 1-(Di(1-aziridinyl)phosphinyl)-3-(5,6-dimethoxy-4-pyrimidinyl)urea
  • 5-[[4,6-Di(1-aziridinyl)-1,3,5-triazin-2-yl]amino]-2-phenyl-1,3-dioxane-5-methanol
  • 5-[[4,6-Di(1-aziridinyl)-1,3,5-triazin-2-yl]amino]-2-(3,4-dimethoxyphenyl)-1,3-dioxane-5-methanol
  • 5-[[4,6-Di(1-aziridinyl)-1,3,5-triazin-2-yl]amino]-2-isopropyl-1,3-dioxane-5-methanol
  • 1,1',1''-Phosphoryltri(2H4)aziridine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • Tert-butyl 4-{[3-(fluorosulfonyl)-5-[(fluorosulfonyl)oxy]-2-methylphenyl]methyl}piperazine-1-carboxylate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide