Pyrrolo[3,4-c]pyridine-1,3-dione

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Names

[ CAS No. ]:
4664-01-1

[ Name ]:
Pyrrolo[3,4-c]pyridine-1,3-dione

[Synonym ]:
1H-Pyrrolo[3,4-c]pyridine-1,3(2H)-dione
Pyrrolo[3,4-c]pyridine-1,3-dione
MFCD00013439
Cinchomeronimide
3,4-Pyridinedicarboximide

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
268.69°C (rough estimate)

[ Melting Point ]:
232-235ºC(lit.)

[ Molecular Formula ]:
C7H4N2O2

[ Molecular Weight ]:
148.119

[ Exact Mass ]:
148.027283

[ PSA ]:
59.06000

[ LogP ]:
-0.34

[ Appearance of Characters ]:
Crystalline Powder | White to tan

[ Index of Refraction ]:
1.623

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7966000
CHEMICAL NAME :
3,4-Pyridinedicarboximide
CAS REGISTRY NUMBER :
4664-01-1
BEILSTEIN REFERENCE NO. :
0124195
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H4-N2-O2
MOLECULAR WEIGHT :
148.13
WISWESSER LINE NOTATION :
T56 BVMV GNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
12500 ug/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 31,172,1976
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
25 mg/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 31,172,1976

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26;S37/S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
US7966000

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cinchomeronic acid
  • Furo[3,4-c]pyridine-1,3-dione
  • Diethyl 3,4-pyridinedicarboxylate
  • 1,3-Diphenylguanidine
  • Acetamide
  • 3,4-Lutidine

DownStream

  • 5-Boc-Octahydro-pyrrolo[3,4-c]pyridine
  • 2-Benzyloctahydro-1H-pyrrolo[3,4-c]pyridine
  • 3-Iodoisonicotinic acid
  • 3-Amino-4-carboxaldehyde
  • 3-Aminoisonicotinic acid
  • methyl 4-((methoxycarbonyl)amino)nicotinate
  • Methyl 3-aminoisonicotinate
  • Ethyl 3-aminoisonicotinate
  • (3-Aminopyridin-4-yl)methanol

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Pyrrolo[3,4-c]pyridine-1,3-dione
  • 2-methylpyrrolo[3,4-c]pyridine-1,3-dione
  • 2-hydroxypyrrolo[3,4-c]pyridine-1,3-dione
  • 2-phenyl-pyrrolo[3,4-c]pyridine-1,3-dione
  • 2-benzyl-pyrrolo[3,4-c]pyridine-1,3-dione
  • 2-hex-1-enylpyrrolo[3,4-c]pyridine-1,3-dione
  • 5-Cyclopropoxy-N,N-dimethyl-2-(trifluoromethyl)pyridin-3-amine
  • N-(2-(4-(furan-2-yl)-1H-imidazol-2-yl)ethyl)isoxazole-5-carboxamide
  • 4-(Azetidin-2-yl)benzene-1,2,3-triol
  • 3-ethyl-1-methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine
  • 1-(4-chlorophenyl)-N-(2-(4-methyl-6-(trifluoromethyl)pyrimidin-2-yl)ethyl)cyclopentanecarboxamide
  • 2-(3,5-Dimethylphenyl)piperazine
  • 2,7-Dimethyl-1-benzothiophene-3-sulfonamide
  • 5-(Diethylsulfamoyl)-4-methoxythiophene-2-carboxylic acid
  • 5-Ethyl-1,2,4-oxadiazole-3-carbaldehyde
  • 1-Cyclopropyl-4-methylpyrrolidin-3-amine