dimethyl 5-isocyanatobenzene-1,3-dicarboxylate

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Names

[ CAS No. ]:
46828-05-1

[ Name ]:
dimethyl 5-isocyanatobenzene-1,3-dicarboxylate

[Synonym ]:
MFCD00037073
dimethyl 5-isocyanatoisophthalate
3,5-dicarbomethoxyphenyl isocyanate
3,5-dimethoxycarbonyl phenyl isocyanate
5-Isocyanato-isophthalsaeure-dimethylester
5-isocyanato-isophthalic acid dimethyl ester
3,5-bis(methoxycarbonyl)phenyl isocyanate

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Boiling Point ]:
350.3ºC at 760 mmHg

[ Melting Point ]:
106-109ºC(lit.)

[ Molecular Formula ]:
C11H9NO5

[ Molecular Weight ]:
235.19300

[ Flash Point ]:
164.1ºC

[ Exact Mass ]:
235.04800

[ PSA ]:
82.03000

[ LogP ]:
1.22710

[ Index of Refraction ]:
1.533

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/22;R36/37/38;R42

[ Safety Phrases ]:
S22-S26-S36/37/39-S45

[ RIDADR ]:
UN 3335

[ HS Code ]:
2929109000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,5-DICARBOMETHOXYANILINE
  • Diphosgene
  • phosgene
  • Dimethyl isophthalate
  • Dimethyl 5-nitroisophthalate

DownStream

Customs

[ HS Code ]: 2929109000

[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Discovery of 14-3-3 Protein-Protein Interaction Inhibitors that Sensitize Multidrug-Resistant Cancer Cells to Doxorubicin and the Akt Inhibitor GSK690693. Mori M, et al.

ChemMedChem 9(5) , 973-983, (2014)


More Articles

Related Compounds

  • dimethyl 5-ethylaminobenzene-1,3-dicarboxylate
  • dimethyl 5-azidobenzene-1,3-dicarboxylate
  • dimethyl 5-hydroxycyclohexane-1,3-dicarboxylate
  • dimethyl 5-sulfamoylbenzene-1,3-dicarboxylate
  • dimethyl 5-chlorosulfonylbenzene-1,3-dicarboxylate
  • dimethyl 5-tert-butylbenzene-1,3-dicarboxylate
  • 1-(1-Ethynylcyclopropyl)-3-trifluoromethanesulfonylbenzene
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-oxo-2,3-dihydro-1H-isoindole-4-carboxylate
  • tert-butyl N-[3-(3-amino-1,1,1-trifluoropropan-2-yl)-4-methoxyphenyl]carbamate
  • 1-[2-Bromo-4-(trifluoromethyl)phenyl]-2-fluoroethan-1-ol
  • (2-Bromo-4,5-difluorophenyl)methanesulfonyl fluoride
  • [1-(3-Bromo-5-chlorophenyl)cyclopropyl]methanol
  • rac-(1R,3R)-3-(2-bromo-4-fluorophenyl)-2,2-dimethylcyclopropane-1-carboxylic acid
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-chloro-5-(ethanesulfonyl)benzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-methyl-3-phenyl-1H-pyrazole-4-carboxylate
  • 1-[3-(methoxycarbonyl)-1-methyl-1H-pyrazol-4-yl]cyclobutane-1-carboxylic acid