oxamide

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Names

[ CAS No. ]:
471-46-5

[ Name ]:
oxamide

[Synonym ]:
Oxalic acid diamide
Diaminoglyoxal
Oxamid
Formimidic acid,1-carbamoyl
Ethanediamide
ethanimidic acid, 2-amino-2-oxo-
Oxamide
MFCD00008007
Oxamimidic acid
EINECS 207-442-5
Ethanedioic Acid Diamide
Oxalamide
2-Amino-2-oxoethanimidic acid
oxalic amide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
262.7±23.0 °C at 760 mmHg

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C2H4N2O2

[ Molecular Weight ]:
88.065

[ Flash Point ]:
112.7±22.6 °C

[ Exact Mass ]:
88.027275

[ PSA ]:
86.18000

[ LogP ]:
-1.96

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.496

[ Water Solubility ]:
insoluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RO4900000
CHEMICAL NAME :
Oxamide
CAS REGISTRY NUMBER :
471-46-5
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C2-H4-N2-O2
MOLECULAR WEIGHT :
88.08
WISWESSER LINE NOTATION :
ZVVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,339,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,10,1953

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
RO4900000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
29241900

Synthetic Route

Precursor & DownStream

Precursor

  • Dimethyl oxalate
  • Methanol
  • carbon monoxide
  • Dithiooxamide
  • OXAMIC ACID
  • Isobutyl chloroformate
  • 5,7-dimethyl-6H-1,4-diazepine-2,3-dicarbonitrile
  • diisopropenyl oxalate
  • 3,4-Dimethoxyphenethylamine

DownStream

  • OXAMIC ACID
  • Benzamide
  • carbonyl sulfide
  • Acetamide
  • 2-Aminoethanol
  • Ethylene glycol
  • 1,2-Ethanediamine
  • N,N'-Diphenylethanediamide
  • N'-phenyloxamide
  • Ethanedioic acid,1,2-bis(2-phenylhydrazide)

Customs

[ HS Code ]: 29241900

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The reaction of lauroyl isothiocyanate and 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile was used to synthesize the title compound 2. Compound 2 could serve as the main building block in ...

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Antibacterial Schiff bases of oxalyl-hydrazine/diamide incorporating pyrrolyl and salicylyl moieties and of their zinc(II) complexes.

J. Enzyme Inhib. Med. Chem. 17(1) , 1-7, (2002)

Schiff bases derived from oxaldiamide/oxalylhydrazine and pyrrol-2-carbaldehyde, or salicylaldehyde respectively, as well as their Zn(II) complexes have been prepared and tested as antibacterial agent...


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Related Compounds

  • Dithioxamide
  • Amino-oxamide
  • methyl-oxamide
  • METHYL OXAMIDE
  • methyl oxamide
  • METHYL OXAMIDE