SB-366791

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
494.2±45.0 °C at 760 mmHg

[ Melting Point ]:
169 °C

[ Molecular Formula ]:
C₁₆H₁₄ClNO₂

[ Molecular Weight ]:
287.741

[ Flash Point ]:
252.7±28.7 °C

[ Exact Mass ]:
287.071320

[ PSA ]:
38.33000

[ LogP ]:
4.52

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.650

[ Storage condition ]:
-20℃

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Involvement of TRPV1 and TRPA1 in incisional intraoral and extraoral pain.

J. Dent. Res. 94(3) , 446-54, (2015)

Thermal and mechanical hypersensitivity in the injured region is a common complication. Although it is well known clinically that thermal and mechanical sensitivity of the oral mucosa is different fro...

Supraspinal TRPV1 modulates the emotional expression of abdominal pain.

Pain 155(10) , 2153-60, (2014)

The transient receptor potential vanilloid receptor type-1 (TRPV1) is critically involved in peripheral nociceptive processes of somatic and visceral pain. However, the role of the capsaicin receptor ...

Acid solution is a suitable medium for introducing QX-314 into nociceptors through TRPV1 channels to produce sensory-specific analgesic effects.

PLoS ONE 6(12) , e29395, (2011)

Previous studies have demonstrated that QX-314, an intracellular sodium channel blocker, can enter into nociceptors through capsaicin-activated TRPV1 or permeation of the membrane by chemical enhancer...

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