Equilin
Suppliers
Names
[ CAS No. ]:
474-86-2
[ Name ]:
Equilin
[Synonym ]:
Equilin
Estra-1,3,5(10),7-tetraen-17-one, 3-hydroxy-
3-Hydroxyestra-1,3,5(10),7-tetraen-17-one (9CI)
Dihydroequilenin
(9S,13S,14S)-3-hydroxy-13-methyl-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-one
3-Hydroxyestra-1,3,5(10),7-tetraen-17-one
1,3,5(10),7-Estratetraen-3-ol-17-one (3-Hydroxy-1,3,5(10),7-estratetraen-17-one
1,3,5,7-Estratetraen-3-ol-17-one
7-Dehydroestrone
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
459.1±45.0 °C at 760 mmHg
[ Melting Point ]:
238-240ºC(lit.)
[ Molecular Formula ]:
C18H20O2
[ Molecular Weight ]:
268.350
[ Flash Point ]:
195.4±21.3 °C
[ Exact Mass ]:
268.146332
[ PSA ]:
37.30000
[ LogP ]:
3.53
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.626
[ Storage condition ]:
-20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KG6650000
- CHEMICAL NAME :
- Estra-1,3,5(10),7-tetraen-17-one, 3-hydroxy-
- CAS REGISTRY NUMBER :
- 474-86-2
- BEILSTEIN REFERENCE NO. :
- 2624302
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H20-O2
- MOLECULAR WEIGHT :
- 268.38
- WISWESSER LINE NOTATION :
- L E5 B666 FV JUTTT&J E1 OQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 112 mg/kg/56W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 640 mg/kg/38W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 168 mg/kg/42W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 48,14,1988
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H351-H360-H362
[ Precautionary Statements ]:
P201-P260-P263-P280-P308 + P313
[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R40
[ Safety Phrases ]:
36/37-45-16-7
[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution
[ WGK Germany ]:
3
[ RTECS ]:
KG6650000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
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