2-(N-cyclohexylcarbamimidoyl)guanidine

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Names

[ CAS No. ]:
4762-22-5

[ Name ]:
2-(N-cyclohexylcarbamimidoyl)guanidine

[Synonym ]:
1-cyclohexylbiguanide monohydrochloride
1-Cyclohexyl-biguanid,Hydrochlorid
1-cyclohexyl-biguanide,hydrochloride

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Boiling Point ]:
374.2ºC at 760 mmHg

[ Molecular Formula ]:
C8H18ClN5

[ Molecular Weight ]:
219.71500

[ Flash Point ]:
180.1ºC

[ Exact Mass ]:
219.12500

[ PSA ]:
97.78000

[ LogP ]:
2.81010

[ Index of Refraction ]:
1.656

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DU1788100
CHEMICAL NAME :
Biguanide, 1-cyclohexyl-, monohydrochloride
CAS REGISTRY NUMBER :
4762-22-5
LAST UPDATED :
199409
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H17-N5.Cl-H
MOLECULAR WEIGHT :
219.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
177 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,117,1974
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 81,3728,1959

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cyclohexanamine hydrochloride (1:1)

DownStream

Related Compounds

  • 2-(N-ethylcarbamimidoyl)guanidine
  • 2-(N,N-dibenzylcarbamimidoyl)guanidine
  • 2-(N-(4-phenylbutyl)carbamimidoyl)guanidine
  • 2-(N-phenanthren-9-ylcarbamimidoyl)guanidine
  • 2-(N-(1-phenylethyl)carbamimidoyl)guanidine
  • 2-(N-(3-methylbutyl)carbamimidoyl)guanidine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 4-Amino-5-hydroxy-3-((2-methyl-4-nitrophenyl)diazenyl)-6-(phenyldiazenyl)-2,7-naphthalenedisulfonic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 8-[(1R)-2-[(1,1-Dimethylethyl)(4-methoxyphenyl)amino]-1-hydroxyethyl]-6-(phenylmethoxy)-2H-1,4-benzoxazin-3(4H)-one
  • N-(2-methylpropyl)-8-thiabicyclo[3.2.1]octan-3-amine
  • benzyl N-(4-chloropyrimidin-2-yl)-N-(2-methylpropyl)carbamate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide