2,2-Bis(hydroxymethyl)propionic acid

Suppliers

Names

[ CAS No. ]:
4767-03-7

[ Name ]:
2,2-Bis(hydroxymethyl)propionic acid

[Synonym ]:
2,2-Bis(Hydroxymethyl)Propanoicacid
2,2-bis(hydroxymethyl)-propionic acid
DiMethylol Propionic
Bis(hydroxymethyl)propionic acid
α, α-Dimethylolpropionic acid
2,2-Bis(hydroxymethyl)propionic Acid
2,2-Bis(hydroxymethyl)propanoic acid
α,α-Bis(hydroxymethyl)propionic acid
2,2-Dimethylolpropionic Acid
3-Hydroxy-2-hydroxymethyl-2-methyl-propionic acid
Bis-MPA
MFCD00004199
Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl-
2,2-BIS(4-CARBOXY-3-NITROPHENYL)HEXAFLUOROPROPANE
3-hydroxyl-2-hydroxymethyl-2-methylpropionic acid
2-carboxy-2-methyl-1,3-propanediol
3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid
Dimethylolpropionic Acid
dihydroxypivalic acid
EINECS 225-306-3
2,2-bis(methylol)propionic acid
DMPA

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
366.7±32.0 °C at 760 mmHg

[ Melting Point ]:
189-191 °C(lit.)

[ Molecular Formula ]:
C5H10O4

[ Molecular Weight ]:
134.130

[ Flash Point ]:
189.7±21.6 °C

[ Exact Mass ]:
134.057907

[ PSA ]:
77.76000

[ LogP ]:
-1.90

[ Vapour density ]:
<1 (vs air)

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.504

[ Stability ]:
Stable. Hygroscopic.

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Hydroxy-2-(Hydroxymethyl)-2-Methylpropionaldehyde
  • 3-acetoxy-2-acetoxymethyl-2-methyl-propionitrile
  • 3-Hydroxy-2-hydroxymethyl-2-methyl-propionic acid methyl ester

DownStream

  • 2-(4-methoxyphenyl)-5-methyl-1,3-dioxane-5-carboxylic acid
  • 5-methyl-2-phenyl-1,3,2-dioxaborinane-5-carboxylic acid
  • 2,2,5-Trimethyl-1,3-dioxane-5-carboxylic Acid
  • Temsirolimus (CCI-779)
  • 2,2-DI(ACETOXYMETHYL)PROPIONYL CHLORIDE
  • bis-mpa-diallyl ether
  • 2,2-BIS-(HYDROXYMETHYL)-PROPANOIC ACID BENZYL ESTER
  • prop-2-ynyl 2,2,5-trimethyl-1,3-dioxane-5-carboxylate
  • ethyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Selenium-Substituted Hydroxyapatite/Biodegradable Polymer/Pamidronate Combined Scaffold for the Therapy of Bone Tumour.

Int. J. Mol. Sci. 16 , 22205-22, (2015)

The present study evaluated a new concept of combined scaffolds as a promising bone replacement material for patients with a bone tumour or bone metastasis. The scaffolds were composed of hydroxyapati...

A chemoselective approach for the accelerated synthesis of well-defined dendritic architectures.

Chem. Commun. (Camb.) , 2249, (2007)

A chemoselective and layered growth approach has been developed for the synthesis of dendrimers, combining Click chemistry with traditional esterification/etherification reactions, without the need fo...

Dendrimers and dendritic polymers in drug delivery.

Drug Discov. Today 10(1) , 35-43, (2005)

The unique properties of dendrimers, such as their high degree of branching, multivalency, globular architecture and well-defined molecular weight, make them promising new scaffolds for drug delivery....


More Articles

Related Compounds

  • 2,2-Bis(hydroxymethyl)propionic acid
  • 2,2-bis(hydroxymethyl)propionic acid sodium salt
  • 2,2-bis-hydroxymethyl-propionic acid isopropyl ester
  • 2,2,5-Trimethyl-1,3-dioxane-5-carboxylic Acid Ethenyl Ester
  • α,α,α-Tris(hydroxymethyl)acetic acid
  • 2,2-BIS-(HYDROXYMETHYL)-PROPANOIC ACID BENZYL ESTER
  • 3-(4-Chlorophenyl)-2,2-dimethylpropanoic acid
  • 2-Fluoro-5-oxiranyl-benzenesulfonamide
  • Ethyl 3,3-difluoro-2-oxopentanoate
  • Thieno[3,4-c]pyrrole-4,6-dione
  • 2-Thiophenesulfonamide,5-[(3-fluorophenyl)thio]-
  • 2-Thiophenesulfonamide,5-[(4-bromophenyl)sulfinyl]-
  • 2-Thiophenesulfonamide,3-chloro-5-(phenylsulfonyl)-
  • 2-Thiophenesulfonamide,4-chloro-5-(phenylsulfonyl)-
  • 5-Phenyl-2-furancarbonyl azide
  • 5-(3-Ethoxy-4-methoxyphenyl)-1-(4-fluorophenyl)-1h-pyrazole