PHA-543613

Names

[ CAS No. ]:
478149-53-0

[ Name ]:
PHA-543613

[Synonym ]:
N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide,hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₇N₃O₂

[ Molecular Weight ]:
271.31

[ Exact Mass ]:
307.10900

[ PSA ]:
58.37000

[ LogP ]:
2.78260

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Furo[2,3-c]pyridine-5-carboxylic acid
(R)-AUINUCLIDIN-3-AMINE HYDROCHLORIDE
3-Aminoquinuclidine dihydrochloride
Furo[2,3-c]pyridine-5-carbaldehyde
Furo[2,3-c]pyridin-5-ylmethanol
2-chlorpyridin-3-ol
2-Chloro-6-(hydroxymethyl)-3-pyridinol
2-Chloro-6-(hydroxymethyl)-4-iodo-3-pyridinol
2-Chloro-6-methoxy-4-[2-(trimethylsilyl)ethynyl]-3-pyridinol

DownStream

Articles

Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis.

J. Immunol. 183(12) , 7787-98, (2009)

Aside from the well-established self-renewal and multipotent differentiation properties, mesenchymal stem cells exhibit both immunomodulatory and anti-inflammatory roles in several experimental autoim...

Immune modulation and increased neurotrophic factor production in multiple sclerosis patients treated with testosterone.

J. Neuroinflammation 5 , 32, (2008)

Multiple sclerosis is a chronic inflammatory disease of the central nervous system with a pronounced neurodegenerative component. It has been suggested that novel treatment options are needed that tar...

Clonal expansions of 6-thioguanine resistant T lymphocytes in the blood and tumor of melanoma patients.

Environ. Mol. Mutagen. 49(9) , 676-87, (2008)

The identification of specific lymphocyte populations that mediate tumor immune responses is required for elucidating the mechanisms underlying these responses and facilitating therapeutic interventio...

PHA-543613 HYDROCHLORIDE
PHA-543613 dihydrochloride
PHA 568487
PHA-793887
PHA-665752
PHA-680632
(2-Chloro-4-cyclopropoxyphenyl)(methyl)sulfane
D-Alanyl-L-prolyl-D-alanyl-L-prolyl-D-alanyl-L-prolyl-D-alanyl-L-proline
(2R)-2,3-Dihydroxypropyl 3-phenylpropanoate
2-Fluoro-5-(3-methyl-1-piperidinylcarbonyl)phenylboronic acid
3-Fluoro-5-(4-bromo-2,6-dichlorophenylcarbamoyl)phenylboronic acid
2-Chloro-5-(cyclohexylcarbamoyl)benzeneboronic acid
3,5-Difluorobenzylmagnesium bromide, 0.25M in 2-MeTHF
2-Chloro-5-(2,5-dichlorophenylcarbamoyl)phenylboronic acid
(3-((2,6-Dimethylphenyl)carbamoyl)-4-fluorophenyl)boronic acid
3-(2,4-Dimethylphenylcarbamoyl)-4-fluorobenzeneboronic acid

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