4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline

Names

[ CAS No. ]:
478698-32-7

[ Name ]:
4,4-Difluoro-3,3-dimethyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}- L-proline

[Synonym ]:
(2S)-4,4-difluoro-3,3-dimethyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
1-hydroxymethyl-4-(4-(1,1-dimethylethoxycarbonyl)piperazinyl)benzene
1-(tert-Butoxycarbonyl)-4-(4-hydroxymethylphenyl)piperazine
4,4-difluoro-3,3-dimethyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
TERT-BUTYL 4-[4-(HYDROXYMETHYL)PHENYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE
(2S)-4,4-difluoro-3,3-dimethyl-N-Boc-proline
4-[4-(methoxycarbonyl)phenyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
1-(tert-butoxycarbonyl)-4-(4-methoxycarbonylphenyl)piperazine
4-(4-N-Boc-piperazinyl)benzyl alcohol
4-(4-methoxycarbonyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
Methyl 4-(N-Boc-N'-piperazinyl)benzoate
1-(tert-butoxycarbonyl)-4,4-difluoro-3,3-dimethylpyrrolidine-2-carboxylic acid
tert-butyl 4-(4-(methoxycarbonyl)phenyl)piperazine-1-carboxylate
tert-butyl 4-(4-(hydroxymethyl)phenyl)piperazine-1-carboxylate

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Boiling Point ]:
348.6ºC at 760 mmHg

[ Molecular Formula ]:
C12H19F2NO4

[ Molecular Weight ]:
279.28000

[ Exact Mass ]:
279.12800

[ PSA ]:
66.84000

[ LogP ]:
2.28970

[ Index of Refraction ]:
1.474

Synthetic Route

Precursor & DownStream

Precursor

  • N-tert-butoxycarbonyl-4,4-difluoro-3,3-dimethylproline methyl ester
  • 1-tert-Butyl 2-methyl 3,3-dimethyl-4-oxopyrrolidine-1,2-dicarboxylate

DownStream


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • Methyl 4-{[4-(tetrahydro-2-furanylmethoxy)benzoyl]amino}benzoate
  • 2-(2-Chloroprop-2-EN-1-YL)bicyclo[2.2.1]heptane-2-carbaldehyde
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • Chelerythrine hydrosulfate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde