tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate

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Names

[ CAS No. ]:
478837-18-2

[ Name ]:
tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate

[Synonym ]:
(3-endo)-tert-butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
3-exo-3-hydroxy-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester
3a-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylic acid t-butyl ester
(1R,3S,5S)-3-hydroxy-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester
3-hydroxy-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester
tert-butyl exo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
Boc-pseudotropine
(1R,3R,5S)-tert-butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
(cis)-3-hydroxy-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester

Chemical & Physical Properties

[ Molecular Formula ]:
C12H21NO3

[ Molecular Weight ]:
227.30000

[ Exact Mass ]:
227.15200

[ PSA ]:
49.77000

[ LogP ]:
1.84710

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-Boc-Nortropinone
  • (1S,5R)-8-azabicyclo[3.2.1]octan-3-ol
  • Di-tert-butyl dicarbonate

DownStream

  • 8-Azabicyclo[3.2.1]octan-3-ol hydrochloride (1:1)

Related Compounds

  • 4-Methoxy-6-{3-[(3-methylpyridin-4-yl)oxy]pyrrolidin-1-yl}pyrimidine
  • 4-Methoxy-2-{3-[(3-methylpyridin-4-yl)oxy]pyrrolidin-1-yl}pyrimidine
  • 2-[4-(3-Methanesulfonylpyridin-2-yl)piperazin-1-yl]-4-methoxypyrimidine
  • 2-Tert-butyl-4-[4-(4,4-difluoropiperidine-1-carbonyl)piperidin-1-yl]pyrimidine
  • 2-{[4-(4,4-Difluoropiperidine-1-carbonyl)piperidin-1-yl]methyl}pyridine
  • 4-{1-[2-(Methylsulfanyl)pyrimidin-4-yl]piperidine-3-carbonyl}morpholine
  • 4-[1-(6-Ethyl-5-fluoropyrimidin-4-yl)piperidine-3-carbonyl]morpholine
  • 4-[4-(6-Tert-butylpyridazin-3-yl)piperazin-1-yl]-6-methyl-2-(pyrrolidin-1-yl)pyrimidine
  • 4-[4-(6-Tert-butylpyridazin-3-yl)piperazin-1-yl]-2-methyl-6-(pyrrolidin-1-yl)pyrimidine
  • 4-[1-(2-Cyclopropyl-6-methylpyrimidin-4-yl)piperidine-3-carbonyl]morpholine
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