Octoclothepin maleate

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Names

[ CAS No. ]:
4789-68-8

[ Name ]:
Octoclothepin maleate

[Synonym ]:
OCTOCLOTHEPIN
OCTOCLOTHEPIN MALEATE SALT
1-(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine maleate salt

Chemical & Physical Properties

[ Molecular Formula ]:
C23H25ClN2O4S

[ Molecular Weight ]:
460.97400

[ Exact Mass ]:
460.12200

[ PSA ]:
106.38000

[ LogP ]:
3.92340

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Risk Phrases ]:
25

[ Safety Phrases ]:
36/37/39-45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ RTECS ]:
TL1575000

Articles

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.

Nat. Commun. 6 , 6555, (2015)

Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires intracellular generation of reactive oxygen species (ROS). We present evidence that macrophage secretion of IL1β upo...

Loss of p53 in stromal fibroblasts enhances tumor cell proliferation through nitric-oxide-mediated cyclooxygenase 2 activation.

Free Radic. Res. 49(3) , 269-78, (2015)

Overexpression of cyclooxygenase 2 (COX-2) by stromal fibroblasts plays a critical role in the early stage of carcinogenesis. COX-2 expression is thought to be positively or negatively regulated by in...

Recombinant thrombomodulin inhibits lipopolysaccharide-induced inflammatory response by blocking the functions of CD14.

J. Immunol. 194(4) , 1905-15, (2015)

CD14, a multiligand pattern-recognition receptor, is involved in the activation of many TLRs. Thrombomodulin (TM), a type I transmembrane glycoprotein, originally was identified as an anticoagulant fa...


More Articles

Related Compounds

  • 3-Fluoro-octoclothepin maleate
  • (E)-but-2-enedioic acid,3-chloro-5-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[b][1]benzothiepine 11,11-dioxide
  • TPN729 maleate
  • lead maleate
  • Dioctyl maleate
  • Dibutyltin Maleate Polymer n=2-3
  • 1-(Aminomethyl)-2-oxabicyclo[3.1.1]heptan-5-amine
  • 3-Amino-4-(propan-2-yloxy)pyridin-2-ol
  • 3-(Pyrrolidin-2-yl)cyclopentan-1-one
  • 3-Tert-butyl-1,2-oxazole-5-sulfonyl fluoride
  • tert-butyl (3R)-3-amino-3-(4-bromophenyl)propanoate
  • 4-Fluoro-6-(2-methylpropoxy)pyrimidin-5-amine
  • (3-Ethyl-1,2-oxazol-5-yl)methanesulfonyl fluoride
  • Ethyl 2-amino-3-(3,5-diaminophenyl)propanoate
  • 2-[(1-Nitrosopyrrolidin-3-yl)oxy]acetic acid
  • Ethyl 2-{6,9-dioxa-2-azaspiro[4.5]decan-7-yl}acetate
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