PIFZER CALCIUM-SENSING PARATHYROID HORMONE RECEPTORS ANTAGONISTS

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Names

[ CAS No. ]:
478963-46-1

[ Name ]:
PIFZER CALCIUM-SENSING PARATHYROID HORMONE RECEPTORS ANTAGONISTS

[Synonym ]:
1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLAMINO)-2(1H)-QUINAZOLINONE
2(1H)-Quinazolinone,1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-ylamino)
6-(propargylamino)-1-isopropyl-4-(4-isopropylphenyl)-1H-quinazolin-2-one

Chemical & Physical Properties

[ Density]:
1.08g/cm3

[ Boiling Point ]:
534.2ºC at 760 mmHg

[ Molecular Formula ]:
C23H25N3O

[ Molecular Weight ]:
359.46400

[ Flash Point ]:
276.9ºC

[ Exact Mass ]:
359.20000

[ PSA ]:
46.92000

[ LogP ]:
4.88590

[ Index of Refraction ]:
1.586

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-Amino-1-isopropyl-4-(4-isopropylphenyl)-2(1H)-quinazolinone
  • 3-Bromopropyne

DownStream

Related Compounds

  • (1R)-1-(2-chloro-4,6-dimethylpyridin-3-yl)-2,2,2-trifluoroethan-1-ol
  • Carbamic acid, [1-(cyanomethyl)-2-phenoxyethyl]-, 1,1-dimethylethyl ester
  • [2-(4-Methoxy-3-nitrophenyl)cyclopropyl]methanamine
  • 5-Amino-1-(2-oxopiperidin-3-yl)-1,2-dihydropyridin-2-one
  • Tert-butyl 4-(1-{[(tert-butoxy)carbonyl]amino}cyclopropyl)-4-hydroxypiperidine-1-carboxylate
  • Tert-butyl 1-{[(tert-butoxy)carbonyl]amino}-4-(hydroxymethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-piperidine]-1'-carboxylate
  • Tert-butyl 3-(1-{[(tert-butoxy)carbonyl]amino}ethyl)-3-hydroxypyrrolidine-1-carboxylate
  • tert-butyl N-{3-[(2-hydroxypropyl)carbamoyl]-1H-pyrazol-4-yl}carbamate
  • Tert-butyl 3-(2-{[(tert-butoxy)carbonyl]amino}ethyl)-3-hydroxypyrrolidine-1-carboxylate
  • Methyl 4-amino-3-(2-ethynylphenyl)butanoate
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