PIFZER CALCIUM-SENSING PARATHYROID HORMONE RECEPTORS ANTAGONISTS

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Names

[ CAS No. ]:
478963-46-1

[ Name ]:
PIFZER CALCIUM-SENSING PARATHYROID HORMONE RECEPTORS ANTAGONISTS

[Synonym ]:
1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLAMINO)-2(1H)-QUINAZOLINONE
2(1H)-Quinazolinone,1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-ylamino)
6-(propargylamino)-1-isopropyl-4-(4-isopropylphenyl)-1H-quinazolin-2-one

Chemical & Physical Properties

[ Density]:
1.08g/cm3

[ Boiling Point ]:
534.2ºC at 760 mmHg

[ Molecular Formula ]:
C23H25N3O

[ Molecular Weight ]:
359.46400

[ Flash Point ]:
276.9ºC

[ Exact Mass ]:
359.20000

[ PSA ]:
46.92000

[ LogP ]:
4.88590

[ Index of Refraction ]:
1.586

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-Amino-1-isopropyl-4-(4-isopropylphenyl)-2(1H)-quinazolinone
  • 3-Bromopropyne

DownStream

Related Compounds

  • Methyl 6-(aminomethyl)-4-(trifluoromethyl)pyridine-2-carboxylate
  • 2H,3H,4H,4aH,5H,9bH-indeno[1,2-b]morpholine hydrochloride
  • 2-(azetidin-3-yloxy)-N,N-dimethylacetamide hydrochloride
  • N-ethylazetidine-3-carboxamide hydrochloride
  • 2-Amino-1-(3,4-difluorophenyl)propan-1-ol hydrochloride
  • 2-Amino-1-(3-fluorophenyl)propan-1-ol hydrochloride
  • Phenylethynesulfonyl chloride
  • N,N-dimethyl-2-(piperidin-4-yloxy)acetamide hydrochloride
  • [1-(Cyclopentyloxy)cyclohexyl]methanamine hydrochloride
  • Methyl 4-(aminomethyl)-6-fluoropyridine-2-carboxylate
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