PIFZER CALCIUM-SENSING PARATHYROID HORMONE RECEPTORS ANTAGONISTS

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Names

[ CAS No. ]:
478963-46-1

[ Name ]:
PIFZER CALCIUM-SENSING PARATHYROID HORMONE RECEPTORS ANTAGONISTS

[Synonym ]:
1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLAMINO)-2(1H)-QUINAZOLINONE
2(1H)-Quinazolinone,1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-ylamino)
6-(propargylamino)-1-isopropyl-4-(4-isopropylphenyl)-1H-quinazolin-2-one

Chemical & Physical Properties

[ Density]:
1.08g/cm3

[ Boiling Point ]:
534.2ºC at 760 mmHg

[ Molecular Formula ]:
C23H25N3O

[ Molecular Weight ]:
359.46400

[ Flash Point ]:
276.9ºC

[ Exact Mass ]:
359.20000

[ PSA ]:
46.92000

[ LogP ]:
4.88590

[ Index of Refraction ]:
1.586

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-Amino-1-isopropyl-4-(4-isopropylphenyl)-2(1H)-quinazolinone
  • 3-Bromopropyne

DownStream

Related Compounds

  • 1-(Chloromethyl)-3-fluoro-5-propylbenzene
  • 3,4-Dimethoxy-5-(pyridin-2-yl)aniline
  • 3-[(2-Ethoxyphenyl)methyl]pyrrolidin-3-ol
  • benzyl N-{2-[(4-bromophenyl)methyl]-1-hydroxypropan-2-yl}carbamate
  • 1-[2-(bromomethyl)pentyl]-4-methanesulfonyl-1H-pyrazole
  • 5-(2-amino-1H-imidazol-5-yl)thiophene-3-carbonitrile
  • 2-[(3-Chlorothiophen-2-yl)oxy]ethan-1-amine
  • (3-Fluorophenyl)(trimethylsilyl)methanone
  • 3-[(3-Chlorothiophen-2-yl)oxy]-3-methylazetidine
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-4-methylpentanoate
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