Lucanthone

Suppliers

Names

[ CAS No. ]:
479-50-5

[ Name ]:
Lucanthone

[Synonym ]:
1-(2-Diethylamino-ethylamino)-4-methylthiaxanthon,Lucanthon
Lycanthone
thioxanthone
1-(2-diethylamino-ethylamino)-4-methyl-thioxanthen-9-one
1-<2-Diaethylamino-aethylamino>-4-methyl-thioxanthenon-(9)
1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one
1-(2-Diaethylamino-aethylamino)-4-methyl-thioxanthen-9-on

Chemical & Physical Properties

[ Density]:
1.184g/cm3

[ Boiling Point ]:
512.4ºC at 760 mmHg

[ Melting Point ]:
195-196ºC

[ Molecular Formula ]:
C₂₀H₂₄N₂OS

[ Molecular Weight ]:
340.48200

[ Flash Point ]:
263.7ºC

[ Exact Mass ]:
340.16100

[ PSA ]:
60.58000

[ LogP ]:
4.54980

[ Vapour Pressure ]:
1.3E-10mmHg at 25°C

[ Index of Refraction ]:
1.638

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XO1605500

CHEMICAL NAME :: Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-methyl-

CAS REGISTRY NUMBER :: 479-50-5

BEILSTEIN REFERENCE NO. :: 0312369

LAST UPDATED :: 199707

DATA ITEMS CITED :: 26

MOLECULAR FORMULA :: C20-H24-N2-O-S

MOLECULAR WEIGHT :: 340.52

WISWESSER LINE NOTATION :: T C666 BS IVJ D1 GM2N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: DNA inhibition

TYPE OF TEST :: Mutation test systems - not otherwise specified

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 6 umol/L

REFERENCE :: PMSBA4 Progress in Molecular and Subcellular Biology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1969- Volume(issue)/page/year: 2,232,1971

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-chloro-4-methyldibenzo[b,e]thiin-10-one
2-aminoethyldiethylamine
Z-1-(2-pyridinyl)-1-propene
2-(Diethylamino)ethanol
5-Chloro-2-methylbenzenethiol
2-Iodo-4-nitrotoluene
5-Chloro-2-methylbenzenesulfonyl chloride
2-((2-methyl-5-nitrophenyl)thio)benzoic acid
2'-carbomethoxy-2-methyl-5-nitro-diphenyl sulfide
2-Chloro-N,N-diethylethanamine