Julolidine

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Names

[ CAS No. ]:
479-59-4

[ Name ]:
Julolidine

[Synonym ]:
2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]chinolin
EINECS 207-535-0
MFCD00006917
1H,5H-Benzo(ij)quinolizine,2,3,6,7-tetrahydro
2,3,6,7-Tetrahydro-1H,5H-benzo(ij)quinolizine
1,2,3,5,6,7-Hexahydropyrido[3,2,1-ij]quinoline
2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline
2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine

Chemical & Physical Properties

[ Density]:
1.1 g/cm3

[ Boiling Point ]:
170-173°C 31mm

[ Melting Point ]:
34-36 °C(lit.)

[ Molecular Formula ]:
C12H15N

[ Molecular Weight ]:
173.25400

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
173.12000

[ PSA ]:
3.24000

[ LogP ]:
2.45040

[ Vapour Pressure ]:
0.000554mmHg at 25°C

[ Index of Refraction ]:
1.568 (25ºC)

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Risk Phrases ]:
52/53

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 8-Hydroxyjulolidine
  • 3-[(3-hydroxypropyl)anilino]-1-propanol
  • 4-Allyljulolidinium iodide
  • 4-Methyl-2,3,4,5,6,7-hexahydro-1H-4lambda~5~-pyrido[3,2,1-ij]quinoline
  • 4-Crotyljulolidinium bromide
  • 1,2,3,4-Tetrahydroquinoline
  • 1-Bromo-3-chloropropane
  • 4-allyl-2,3,4,5,6,7-hexahydro-1H-pyrido[3,2,1-ij]quinolin-4-ium bromide

DownStream

  • 9-Julolidinecarboxaldehyde
  • 9-bromo-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-IJ]quinoline
  • 2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-methanol
  • 1H,5H-Benzo(ij)quinolizinium, 2,3,6,7-tetrahydro-9-(hydroxymethyl)-4-m ethyl-, iodide
  • 2,3,6,7,2',3',6',7'-octahydro-1H,5H,1'H,5'H-[9,9']bi[pyrido[3,2,1-ij]quinolinyl]
  • 4-Methyl-2,3,4,5,6,7-hexahydro-1H-4lambda~5~-pyrido[3,2,1-ij]quinoline

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Characterization and Higher-Order Structure Assessment of an Interchain Cysteine-Based ADC: Impact of Drug Loading and Distribution on the Mechanism of Aggregation.

Bioconjug. Chem. 27 , 604-15, (2016)

The impact of drug loading and distribution on higher order structure and physical stability of an interchain cysteine-based antibody drug conjugate (ADC) has been studied. An IgG1 mAb was conjugated ...


More Articles

Related Compounds

  • 4-Bromojulolidine
  • 9-Cyanojulolidine
  • 9-Methyljulolidine
  • julolidinecarbaldehyde
  • Julolidine hydrobromide
  • julolidine-9-methanamine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • Methyl({4-methylbicyclo[2.2.1]heptan-1-yl}methyl)amine
  • 3-Bromo-2-(m-tolyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine