1,5-dimethyl-2-phenylpyrazol-3-one,2,2,2-trichloroethane-1,1-diol

Names

[ CAS No. ]:
480-30-8

[ Name ]:
1,5-dimethyl-2-phenylpyrazol-3-one,2,2,2-trichloroethane-1,1-diol

[Synonym ]:
Kloralfenazon
Sominat
Dichloralantipyrin
Sedor
dichloralphenazone
Dormuphar
Welldorm
Dichloralantipyrine
Ibiodorm

Chemical & Physical Properties

[ Boiling Point ]:
319ºC at 760 mmHg

[ Molecular Formula ]:
C15H18Cl6N2O5

[ Molecular Weight ]:
519.03200

[ Exact Mass ]:
515.93500

[ PSA ]:
107.85000

[ LogP ]:
2.81900

[ Vapour Pressure ]:
0.000348mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CD2600000
CAS REGISTRY NUMBER :
480-30-8
LAST UPDATED :
198507
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H12-N2-O.2C2-H3-Cl3-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1338 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,137,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1437 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,137,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
982 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,137,1956

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Antipyrine
  • Chloral

DownStream

Related Compounds

  • 2-[1-({[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)furan-2-yl]formamido}methyl)cyclobutyl]acetic acid
  • 2-({4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-3-hydroxy-2-methylpropanoic acid
  • tert-Butyl (4-(cyanomethoxy)butyl)carbamate
  • (5-(2)H)-1,3-thiazol-2-amine
  • 2,2-Difluoro-1-{3-[(trifluoromethyl)sulfanyl]phenyl}ethan-1-amine
  • 2,2,2-trifluoro-1-[3-(1H-1,2,3,4-tetrazol-5-yl)phenyl]ethan-1-amine
  • 2-methyl-4-(1-phenyl-1H-1,2,3-triazol-4-yl)butan-2-amine
  • 3-[3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl]piperidine
  • 2-Cyclopropyl-4-formylbenzonitrile
  • 3-(4-Bromo-3-fluorophenyl)-1,1-difluoro-2-methylpropan-2-amine
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