Ochratoxin B
Suppliers
Names
[ CAS No. ]:
4825-86-9
[ Name ]:
Ochratoxin B
[Synonym ]:
OCHRATOXIN B
Ochratoxin B solution
ochratoxin A
N-{[(3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl]-carbonyl}-L-phenylalanine
N-{[(3R)-8-Hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl]carbonyl}-L-phenylalanine
Alanine,N-((8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenyl-,(-)
N-{[(3R)-8-hydroxy-3-methyl-1-oxo-7-isochromanyl]carbonyl}-3-phenyl-L-alanine
(R)-N-[(3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carboxyl]phenylalanine
L-Phenylalanine, N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-
L-Phenylalanine,N-((3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl)-,(R)
Ochratoxin B(OTB)
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
632.4±55.0 °C at 760 mmHg
[ Melting Point ]:
221ºC
[ Molecular Formula ]:
C20H19NO6
[ Molecular Weight ]:
369.368
[ Flash Point ]:
336.2±31.5 °C
[ Exact Mass ]:
369.121246
[ PSA ]:
112.93000
[ LogP ]:
3.06
[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C
[ Index of Refraction ]:
1.623
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY6825000
- CHEMICAL NAME :
- Alanine, N-((8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl) -3-phenyl-, (-)-
- CAS REGISTRY NUMBER :
- 4825-86-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H19-N-O6
- MOLECULAR WEIGHT :
- 369.40
- WISWESSER LINE NOTATION :
- T66 BVOT&J D1 IVMYVQ1R& JQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 54 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Primate - monkey Kidney
- DOSE/DURATION :
- 20 mg/L
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 32,198,1975
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H302-H312-H319-H332
[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338
[ Hazard Codes ]:
Xn,T,F
[ Risk Phrases ]:
22-36/37/38-65-48/23/24/25-36/38-11-46-45
[ Safety Phrases ]:
26-36-45-16-53
[ RIDADR ]:
UN 3462 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
AY6825000
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
39229000
Synthetic Route
Articles
Toxins (Basel.) 4(12) , 1535-51, (2012)
It has previously been shown that the biosynthesis of the mycotoxins ochratoxin A and B and of citrinin by Penicillium is regulated by light. However, not only the biosynthesis of these mycotoxins, bu...
J. Chromatogr. A. 864(1) , 89-101, (1999)
A new and accurate method to quantify ochratoxin A (OA) in table wine has been developed. The method uses commercial immunoaffinity columns for clean-up and high-performance liquid chromatography (HPL...
Anal. Bioanal. Chem 400(8) , 2615-22, (2011)
The paper presents a new sample clean-up method based on immuno-ultrafiltration for the analysis of ochratoxin A in cereals. In contrast to immunoaffinity chromatography, in immuno-ultrafiltration, th...