2-chlorocyclooctan-1-one

Names

[ CAS No. ]:
4828-34-6

[ Name ]:
2-chlorocyclooctan-1-one

[Synonym ]:
2-chloro-cyclooctanone
2-Chlorcyclo-octanon
Cyclooctanone,2-chloro
2-chloro-cyclooctan-1-one
2-Chlor-cyclooctan-1-on

Chemical & Physical Properties

[ Density]:
1.06g/cm3

[ Boiling Point ]:
253.7ºC at 760 mmHg

[ Molecular Formula ]:
C8H13ClO

[ Molecular Weight ]:
160.64100

[ Flash Point ]:
122.3ºC

[ Exact Mass ]:
160.06500

[ PSA ]:
17.07000

[ LogP ]:
2.51710

[ Index of Refraction ]:
1.465

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY0175000
CHEMICAL NAME :
Cyclooctanone, 2-chloro-
CAS REGISTRY NUMBER :
4828-34-6
BEILSTEIN REFERENCE NO. :
1929892
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H13-Cl-O
MOLECULAR WEIGHT :
160.66
WISWESSER LINE NOTATION :
L8VTJ BG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1040 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - analgesia
REFERENCE :
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 254,2683,1962

Safety Information

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
36/37/39

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • cycloocten-1-yloxy(trimethyl)silane
  • Cyclooctene
  • Carbamic acid,methylnitro-, methyl ester (7CI,8CI,9CI)
  • Cyclooctanone
  • Ethylene glycol
  • 2-phenylselanylcyclooctan-1-one
  • Cyclooctane
  • 1-(dichloromethyl)cycloheptan-1-ol

DownStream

  • 2-hydroxycyclooctan-1-one
  • Dimethyl octanedioate
  • Cyclooctanone
  • Cycloheptanecarboxylic acid
  • Methyl cycloheptanecarboxylate
  • 4,5,6,7,8,9-Hexahydro-1H-cycloocta[d]imidazole
  • 2-methylsulfanylcyclooctan-1-one

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Related Compounds

  • 2-stearoylcyclohexan-1-one
  • 2-Propen-1-one,1-(4-bromophenyl)-2-(1-piperidinylmethyl)-, hydrochloride (1:1)
  • 2-Propen-1-one,1-(2-hydroxyphenyl)-3-(2-pyridinyl)-
  • 2-phenylsulfanylphthalazin-1-one
  • 2-PROPEN-1-ONE, 1-(2-HYDROXY-3,4-DIMETHOXYPHENYL)-3-(2,3,4-TRIMETHOXYPHENYL)-
  • 2-methylcyclopentadecan-1-one