(4R,4aS,7S,7aR,12bS)-9-methoxy-3-methyl-1,2,4,7,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol

Names

[ Name ]:
(4R,4aS,7S,7aR,12bS)-9-methoxy-3-methyl-1,2,4,7,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol

[Synonym ]:
14-Hydroxycodeine
14-Hydroxy-codein
(5α,6α)-3-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6,14-diol
14-hydroxydihydrocodeine
Morphinan-6,14-diol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
506.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₁NO₄

[ Molecular Weight ]:
315.364

[ Flash Point ]:
260.0±30.1 °C

[ Exact Mass ]:
315.147064

[ PSA ]:
62.16000

[ LogP ]:
1.03

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.695

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

14-Hydroxy Codeinone
(-)-codeine
(+)-14β-bromocodeinone
thebaine
6α-acetoxy-4,5α-epoxy-3-methoxy-17-methyl-morphin-7-en-14-ol
14-hydroxycodeine diacatate

DownStream

14-Hydroxy Codeinone
6α-Oxymorphol
oxycodone
[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] pentanoate
dimethyl 2,3-diphenoxybutanedioate
[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate

Related Compounds

3,4,5-Tris(trifluoromethyl)bromobenzene
2-(3-Chloro-1-benzothien-2-yl)-5-(chloromethyl)-1,3,4-oxadiazole
4-cyano-N-(2-(4-(6-fluorobenzo[d]thiazol-2-yl)piperazin-1-yl)ethyl)benzamide hydrochloride
3-[4-(Benzyloxy)phenyl]-3-hydroxypropanoic acid
Cyclohexyl(cyclopentyl)methanone
N1-(3-bromophenyl)-1,3-Propanediamine
5-Morpholin-4-yl-nicotinic acid tert-butyl ester
5-methoxy-3-methyl-2,3-dihydro-1H-inden-1-one
4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl trifluoromethanesulfonate
1,3,6,7-Tetrahydro-2H-azepin-2-on