4-(Difluoromethoxy)benzoic acid

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Names

[ CAS No. ]:
4837-20-1

[ Name ]:
4-(Difluoromethoxy)benzoic acid

[Synonym ]:
QVR DOYFF
MFCD00221454
Benzoic acid, 4-(difluoromethoxy)-
4-(Difluoromethoxy)benzoic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
272.1±30.0 °C at 760 mmHg

[ Melting Point ]:
169-171 °C(lit.)

[ Molecular Formula ]:
C8H6F2O3

[ Molecular Weight ]:
188.128

[ Flash Point ]:
118.3±24.6 °C

[ Exact Mass ]:
188.028503

[ PSA ]:
46.53000

[ LogP ]:
2.14

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.497

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918990090

Synthetic Route

Precursor & DownStream

Precursor

  • 1-(Difluoromethoxy)-4-methylbenzene

DownStream

  • 4-(Difluoromethoxy)benzohydrazide

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Synthetic Applications of Difluorocarbene I. The Preparation of Some Aryl Difluoromethyl Ethers, Thioethers and Sulphones. De Cat A, et al.

Bull. Soc. Chim. Belg. 74(5-6) , 270-80, (1965)


More Articles


Related Compounds

  • 3-Bromo-4-(difluoromethoxy)benzoic acid
  • 2-Chloro-4-(difluoromethoxy)benzoic acid
  • 3-cyclopropyloxy-4-(difluoromethoxy)benzoic acid
  • 3-hydroxy-4-(difluoromethoxy)benzoic acid methyl ester
  • 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid
  • 4-DIFLUOROMETHOXY-3-METHOXY-BENZOIC ACID
  • Imidazo[1,2-a]pyridin-3-amine, 6-fluoro-7-methyl-
  • 2-Amino-4,6-difluoro-N-hydroxybenzimidamide
  • 7-Bromo-6-chloroimidazo[1,2-a]pyridin-3-amine
  • Imidazo[1,2-a]pyridin-3-amine, 7-bromo-8-fluoro-
  • 6-Chloro-N-(4-cyclopropyl-1,2,4-triazol-3-yl)-3,4-dihydro-2H-chromene-4-carboxamide
  • Nicofluprole
  • Imidazo[1,2-a]pyridine-6-carbonitrile, 3-amino-7-methoxy-
  • 4-Cyclopropyl-N-[1-(4-fluorophenyl)-2-oxoazetidin-3-yl]-1,3-oxazole-5-carboxamide
  • 4-Fluoro-7-methoxy-1,3-benzodioxole
  • 5-(2,5-dichlorophenyl)-N-[(Z)-(3-hydroxyphenyl)methylideneamino]pyrazolidine-3-carboxamide
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