FURO(2,3-b)QUINOLINE, 4,6,7-TRIMETHOXY-

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Names

[ CAS No. ]:
484-08-2

[ Name ]:
FURO(2,3-b)QUINOLINE, 4,6,7-TRIMETHOXY-

[Synonym ]:
skimmianine
Dictamnine,6,7-dimethoxy
Kokusaginin
6,7-Dimethoxydictamnine
Kokusaginine
kokusagenine
kokusagenin

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
401.6ºC at 760 mmHg

[ Molecular Formula ]:
C14H13NO4

[ Molecular Weight ]:
259.25700

[ Flash Point ]:
196.7ºC

[ Exact Mass ]:
259.08400

[ PSA ]:
53.72000

[ LogP ]:
3.00680

[ Vapour Pressure ]:
2.7E-06mmHg at 25°C

[ Index of Refraction ]:
1.621

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LV2798000
CHEMICAL NAME :
Furo(2,3-b)quinoline, 4,6,7-trimethoxy-
CAS REGISTRY NUMBER :
484-08-2
BEILSTEIN REFERENCE NO. :
0256613
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H13-N-O4
MOLECULAR WEIGHT :
259.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
2760 ng/plate
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 2,271,1987

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (+)-1-[(4,6-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-2,3-butanediol
  • 4,6-dimethoxy-9H-furo[2,3-b]quinolin-7-one
  • Dimethyl sulfate

DownStream

  • 1,3-Dioxolo[4,5-g]furo[2,3-b]quinoline,9-methoxy-

Related Compounds

  • 4,6,7-trimethoxyfuro[2,3-b]quinoline,trihydrate
  • 4,6,7-trimethoxy-5-methylchromen-2-one
  • 9-chloro-4-methoxy-[1,3]dioxolo[4,5-g]furo[2,3-b]quinoline
  • Maculosidin
  • Skimmianin
  • 4,6,7,8-tetramethoxy-furo[2,3-b]quinoline
  • 4-methyl-1-({1-[(2-methylphenyl)methyl]azetidin-3-yl}methyl)-1H-pyrazole
  • 3-methoxy-N-{[1-(6-methoxypyrimidin-4-yl)piperidin-4-yl]methyl}-N-methylpyrazin-2-amine
  • 2-(4-{[(3-Methoxypyrazin-2-yl)(methyl)amino]methyl}piperidin-1-yl)-4,6-dimethylpyridine-3-carbonitrile
  • 5,6-dimethyl-3-{2-[5-(1-methyl-1H-1,3-benzodiazol-2-yl)-octahydropyrrolo[3,4-c]pyrrol-2-yl]-2-oxoethyl}-3,4-dihydropyrimidin-4-one
  • 9-methyl-6-[4-({4-[4-(propan-2-yl)piperazin-1-yl]but-2-yn-1-yl}oxy)piperidin-1-yl]-9H-purine
  • 5-Chloro-2-(3-{[(4-cyanopyridin-2-yl)oxy]methyl}piperidin-1-yl)-4,6-dimethylpyridine-3-carbonitrile
  • 5-Chloro-2-(4-{[(4-cyanopyridin-2-yl)oxy]methyl}piperidin-1-yl)-4,6-dimethylpyridine-3-carbonitrile
  • 5-Chloro-2-({1-[(2,4-difluorophenyl)methyl]piperidin-4-yl}oxy)pyrimidine
  • 2-[4-({4-[4-(propan-2-yl)piperazin-1-yl]but-2-yn-1-yl}oxy)piperidin-1-yl]-5H,7H,8H-pyrano[4,3-b]pyridine-3-carbonitrile
  • 4-({1-[(3,4-Dimethoxyphenyl)methyl]azetidin-3-yl}oxy)pyridine
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