dihydralazine

Suppliers

Names

[ CAS No. ]:
484-23-1

[ Name ]:
dihydralazine

[Synonym ]:
1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone
Dihydralazin
Nepresol
1,4-dihydrazinophthanazine
1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone, (1Z,4Z)-
1,4-Dihydrazinophthalazine
Nepresolin
Dihydrallazine
Dihydrallazin
4-Hydrazino-1-hydrazono-1,2-dihydrophthalazine
phthalazine, 1,4-bis(hydrazino)-
Phthalazine, 1,4-bis(hydrazinyl)-
1,4-dihydrazinophtalazine
(1Z,4E)-1,4-Dihydrazono-1,2,3,4-tetrahydrophthalazine
Nepressol
Hypopresol
1,4-bis(hydrazino)phthalazine
1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone, (1Z,4E)-
(1Z,4Z)-1,4-Dihydrazono-1,2,3,4-tetrahydrophthalazine
Ophthazin
dihydralazine
1,4-dihydrazinylphthalazine

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
419.9±28.0 °C at 760 mmHg

[ Melting Point ]:
180ºC

[ Molecular Formula ]:
C8H10N6

[ Molecular Weight ]:
190.205

[ Flash Point ]:
207.7±24.0 °C

[ Exact Mass ]:
190.096695

[ PSA ]:
108.34000

[ LogP ]:
0.73

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.810

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TH8849900
CHEMICAL NAME :
Phthalazine, 1,4-dihydrazino-
CAS REGISTRY NUMBER :
484-23-1
BEILSTEIN REFERENCE NO. :
0183442
LAST UPDATED :
199703
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C8-H10-N6
MOLECULAR WEIGHT :
190.24
WISWESSER LINE NOTATION :
T66 CNNJ BMZ EMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
106 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
250 ug/kg
SEX/DURATION :
female 32 week(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
125 ug/tube
REFERENCE :
ABPLAF Acta Biochimica Polonica. (Polish Biochemical Society, Posteura 3, 01-093 Warsaw, Poland) V.1- 1954- Volume(issue)/page/year: 42,291,1995

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Phthalonitrile
  • 1,4-Dichlorophthalazine
  • 1-chloro-4-methoxyphthalazine
  • 1-ETHOXY-4-CHLOROPHTHALAZINE
  • 1-Chloro-4-hydrazinophthalazine
  • Phthalimide diimide
  • 1,4-Dimercapto phthalazine
  • 2,3-Dihydrophthalazine-1,4-dione
  • Phthalic acid

DownStream

  • N,N-bis[(2-chlorophenyl)methylideneamino]phthalazine-1,4-diamine
  • Benzaldehyde, 2,6-dichloro-, 1,4-phthalazinediyldihydrazone(8CI,9CI)
  • 2-Propenal, 3-phenyl-,1,4-phthalazinediyldihydrazone (9CI)
  • Benzaldehyde, 3-nitro-,1,4-phthalazinediyldihydrazone (9CI)
  • Benzaldehyde,4-chloro-, 1,4-phthalazinediyldihydrazone (9CI)
  • Benzaldehyde, p-nitro-,1,4-phthalazinediyldihydrazone (8CI)
  • 5-Nitrophthalazine
  • 5-Aminophthalazine
  • Phthalazine
  • Benzaldehyde,2-methoxy-, 1,4-phthalazinediyldihydrazone (9CI)

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • dihydralazine
  • Dihydralazine mesylate
  • Dihydralazine tartrate
  • dihydralazine salicyldehyde
  • dihydralazine hydrochloride
  • Dihydralazine sulfate,hydrated
  • methyl 2-amino-2-(1-methyl-1H-indol-6-yl)acetate
  • 1-(Cyclopropanesulfonyl)-4-[3-(pyridin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-1,4-diazepane
  • 8-(2-Chlorophenyl)-6-azaspiro[3.4]octane
  • 2,2-Difluoro-1-methylcyclohexane-1-carbonitrile
  • 4-Methoxy-5-methyl-1,3-thiazole-2-carbaldehyde
  • Ethyl 2-(3-methylpyridin-4-yl)propanoate
  • 5-(9H-Fluoren-9-ylmethoxycarbonyl)-8-oxa-5-azaspiro[3.5]nonane-7-carboxylic acid
  • 6-Methoxy-4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]-2,3-dihydroindole-2-carboxylic acid
  • (4aR,7aS)-octahydro-1H-pyrrolo[3,4-b]piperazine-2,3-dione
  • 2-Bromo-5-fluoro-4-(trifluoromethyl)benzamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.