carbinoxamine

Suppliers

Names

[ CAS No. ]:
486-16-8

[ Name ]:
carbinoxamine

[Synonym ]:
Carbinoxamina
2-[(4-chlorophenyl)-pyridin-2-ylmethoxy]-N,N-dimethylethanamine
Rotoxamine
2-((4-Chlorophenyl)(pyridin-2-yl)methoxy)-N,N-dimethylethanamine
Carbinoxaminum
Clistin
(+/-)-Carbinoxamine
McN-R 73Z
Allergefon

Chemical & Physical Properties

[ Density]:
1.143g/cm3

[ Boiling Point ]:
381.1ºC at 760mmHg

[ Molecular Formula ]:
C16H19ClN2O

[ Molecular Weight ]:
290.78800

[ Flash Point ]:
184.3ºC

[ Exact Mass ]:
290.11900

[ PSA ]:
25.36000

[ LogP ]:
3.40260

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US6330000
CHEMICAL NAME :
Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)-
CAS REGISTRY NUMBER :
486-16-8
BEILSTEIN REFERENCE NO. :
0250475
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H19-Cl-N2-O
MOLECULAR WEIGHT :
290.82
WISWESSER LINE NOTATION :
T6NJ BYR DG&O2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00940

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • carbinoxamine N-oxide
  • Pyridine
  • (2-Chloroethyl)dimethylamine hydrochloride
  • 4-Chlorobenzaldehyde
  • 2-Chloroethyldimethylamine
  • 4-Chlorophenyl-2-pyridinylmethanol

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • carbinoxamine
  • (S)-carbinoxamine
  • (±)-Carbinoxamine-d6
  • carbinoxamine N-oxide
  • carbinoxamine maleate
  • 3-(3-Chloro-5-fluorophenyl)-1,2,4-oxadiazole
  • (3-Methyl-5-(methylthio)phenyl)methanol
  • Tert-butyl 8-azaspiro[4.5]decane-8-carboxylate
  • 1-(tert-Butyl) 3-methyl 3-(methoxymethyl)azetidine-1,3-dicarboxylate
  • 1-[(Tert-butoxy)carbonyl]-3-(methoxymethyl)pyrrolidine-3-carboxylic acid
  • 2-(5-Chloro-2-fluorophenyl)azetidine
  • 1-(2-Hydroxy-2-methylpropyl)guanidine
  • 2-Phenylpyrrolidine-2-carboxylic acid hydrochloride
  • [2-(2-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid hydrochloride
  • 1-Phenyl-N-(1,3-thiazol-2-ylmethyl)methanamine dihydrochloride
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