Hydroxyprocaine
Suppliers
Names
[ CAS No. ]:
487-53-6
[ Name ]:
Hydroxyprocaine
[Synonym ]:
4-Amino-2-hydroxy-benzoesaeure-(2-diaethylamino-aethylester)
Metahydroxyprocaine
Oxyprocain
Hydroxyprocaine
Oxycaine
Hydroxynovocain
2-Diethylaminoethyl p-aminosalicylate
4-Amino-salicylsaeure-(2-diethylamino-ethylester)
Oxyprocaine
m-Hydroxyprocaine
Oxiprocainum
4-Amino-2-hydroxy-benzoesaeure-(2-diethylamino-ethylester)
p-Amino-salicylsaeure-diaethylaminoaethyl-ester
Hydroxy-procain
4-amino-2-hydroxy-benzoic acid-(2-diethylamino-ethyl ester)
Diethylaminoethyl p-aminosalicylate
MFCD00047845
Chemical & Physical Properties
[ Density]:
1.158g/cm3
[ Boiling Point ]:
408.7ºC at 760mmHg
[ Molecular Formula ]:
C13H20N2O3
[ Molecular Weight ]:
252.30900
[ Flash Point ]:
201ºC
[ Exact Mass ]:
252.14700
[ PSA ]:
75.79000
[ LogP ]:
2.05420
[ Vapour Pressure ]:
2.9E-07mmHg at 25°C
[ Index of Refraction ]:
1.565
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VO1575000
- CHEMICAL NAME :
- Salicylic acid, 4-amino-, 2-(diethylamino)ethyl ester
- CAS REGISTRY NUMBER :
- 487-53-6
- BEILSTEIN REFERENCE NO. :
- 2650192
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C13-H20-N2-O3
- MOLECULAR WEIGHT :
- 252.35
- WISWESSER LINE NOTATION :
- ZR CQ DVO2N2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 190 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 36 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 2,112,1952
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 47 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 72 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 10,284,1951
Safety Information
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%