Icariin

Names

[ CAS No. ]:
489-32-7

[ Name ]:
Icariin

[Synonym ]:
ICARRIN
ICARIN
Icariin
Ieariline
Icariil
ICARIINE
Epimedim P.E
Icariln
Icraiin
4'-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
948.5±65.0 °C at 760 mmHg

[ Melting Point ]:
223-225ºC

[ Molecular Formula ]:
C₃₃H₄₀O₁₅

[ Molecular Weight ]:
676.662

[ Flash Point ]:
300.9±27.8 °C

[ Exact Mass ]:
676.236694

[ PSA ]:
238.20000

[ LogP ]:
2.48

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.679

MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932999099

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Icariin promotes histone acetylation and attenuates post-stroke cognitive impairment in the central cholinergic circuits of mice.

Neuroscience 236 , 281-8, (2013)

Post-stroke dementia (PSD) is a common clinical disease and the central cholinergic circuits are important to cognitive function. Icariin (ICA), a flavonoid isolated from Herba Epimedii, was reported ...

High-performance liquid chromatography-based multivariate analysis to predict the estrogenic activity of an Epimedium koreanum extract.

Biosci. Biotechnol. Biochem. 76(5) , 923-7, (2012)

This study characterizes the correlation between the chemical fingerprint and estrogenic activity of an Epimedium koreanum extract. The estrogenic activity of 31 E. koreanum extract samples was evalua...

Inhibitory effect of icariin on Ti-induced inflammatory osteoclastogenesis.

J. Surg. Res. 192(2) , 447-53, (2014)

Wear particle-induced periprosthetic osteolysis that results in aseptic loosening is the most common cause of long-term failure after total joint replacement.Icariin (ICA), a flavonoid isolated from E...