5-Chloro-1-methyl-4-nitroimidazole

Suppliers

Names

[ Name ]:
5-Chloro-1-methyl-4-nitroimidazole

[Synonym ]:
1-methyl-5-chloro-4-nitroimidazole
PCMNI
1-methyl-4-nitro-5-chloroimidazole
5-chloro-1-methyl-4-nitro-imidazole
5-Chloro-1-methyl-4-nitro-1H-imidazole
5-Chloro-1-methyl-4-nitroimidazole
MFCD00233664
1H-Imidazole, 5-chloro-1-methyl-4-nitro-
5-Chloro-1-methyl-4-nitroimidazole (AZATHIOPRINUM)
Imidazole,5-chloro-1-methyl-4-nitro
EINECS 225-521-2
1H-Imidazole,5-chloro-1-methyl-4-nitro
1-METHYL-5-CHLORO-4-NITRO IMIDAZOLE

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
362.3±22.0 °C at 760 mmHg

[ Melting Point ]:
148-150 °C(lit.)

[ Molecular Formula ]:
C₄H₄ClN₃O₂

[ Molecular Weight ]:
161.55

[ Flash Point ]:
172.9±22.3 °C

[ Exact Mass ]:
160.999207

[ PSA ]:
63.64000

[ LogP ]:
0.50

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.648

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI4397100

CHEMICAL NAME :: Imidazole, 5-chloro-1-methyl-4-nitro-

CAS REGISTRY NUMBER :: 4897-25-0

BEILSTEIN REFERENCE NO. :: 0136775

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C4-H4-Cl-N3-O2

MOLECULAR WEIGHT :: 161.56

WISWESSER LINE NOTATION :: T5N CNJ A1 DNW EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 umol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,1,1978

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NI4397100

[ HS Code ]:
2933290090

Precursor & DownStream

Precursor

DownStream

guaneran
5-METHOXY-1-METHYL-3-NITRO-1H-IMIDAZOLE
Piperidine,1-(1-methyl-4-nitro-1H-imidazol-5-yl)-
1-Methyl-2,4,5-imidazolidinetrione
1-methyl-5-methylsulfanyl-4-nitro-imidazole
1-methyl-4-nitro-5-phenylimidazole
Acetic acid,2-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-, ethyl ester
Propanedioic acid,2-(1-methyl-4-nitro-1H-imidazol-5-yl)-, 1,3-diethyl ester
N-benzyl-3-methyl-5-nitroimidazol-4-amine
1-Methyl-4-nitro-1H-imidazol-5-amine

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

New synthesis and antiparasitic activity of model 5-aryl-1-methyl-4-nitroimidazoles.

Molecules 14(8) , 2758-67, (2009)

A number of 5-aryl-1-methyl-4-nitroimidazoles 5a-f have been synthesized in good yields by the Suzuki coupling reaction between 5-chloro-1-methyl-4-nitroimidazole (3) and arylboronic acids 4a-f, aided...

Rapid-mix studies on the anomalous radiosensitization of mammalian cells by 5-chloro-1-methyl-4-nitromidazole.

Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 38(6) , 673-5, (1980)

The kinetics of the reaction of 'anomalous' 4-nitroimidazole radiosensitizers with thiols.

Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 41(2) , 231-5, (1982)

5-Chloro-1-methyl-4-nitro-1H-pyrazole
3-(bromomethyl)-5-chloro-1-methyl-4-nitropyrazole
1H-Pyrazole-3-carboxylic acid, 5-chloro-1-methyl-4-nitro-
5-dichloromethyl-1-methyl-4-nitroimidazole
5-chloro-1-ethyl-2-methyl-4-nitro-imidazole
5-Chloro-1-methyl-3-(4-methylphenyl)-1H-pyrazole