Hydroxytetracaine
Suppliers
Names
[ CAS No. ]:
490-98-2
[ Name ]:
Hydroxytetracaine
[Synonym ]:
Salicacaine
Oxypentocain
Salicain
Idrossitetracaina [DCIT]
Oxitetracainum
4-Butylamino-2-hydroxy-benzoesaeure-(2-dimethylamino-aethylester)
Salicaine (anesthetic)
Hydroxytetracain
Hydroxamethocaine
Rhenocain
Hydroxytetracainum [INN-Latin]
4-butylamino-2-hydroxy-benzoic acid-(2-dimethylamino-ethyl ester)
Hydroxytetracaine
Chemical & Physical Properties
[ Density]:
1.114g/cm3
[ Boiling Point ]:
415.1ºC at 760mmHg
[ Molecular Formula ]:
C15H24N2O3
[ Molecular Weight ]:
280.36300
[ Flash Point ]:
204.9ºC
[ Exact Mass ]:
280.17900
[ PSA ]:
61.80000
[ LogP ]:
2.39560
[ Vapour Pressure ]:
1.76E-07mmHg at 25°C
[ Index of Refraction ]:
1.557
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VO1932000
- CHEMICAL NAME :
- Salicylic acid, p-(butylamino)-, 2-(dimethylamino)ethyl ester
- CAS REGISTRY NUMBER :
- 490-98-2
- BEILSTEIN REFERENCE NO. :
- 2125583
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C15-H24-N2-O3
- MOLECULAR WEIGHT :
- 280.41
- WISWESSER LINE NOTATION :
- 4MR DQ CVO2N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intratracheal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 2,112,1952
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 22 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 104,40,1952