2,3,4,5-tetrachlorophenol

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Names

[ CAS No. ]:
4901-51-3

[ Name ]:
2,3,4,5-tetrachlorophenol

[Synonym ]:
2,3,4,5-tetrachlorophenol solution
2,3,4,5-TECP
2,3']BITHIOPHENYL-5-CARBALDEHYDE
2,3,4,5-tetrachlorophenol
2,3,4,5-tetrachloro-phenol
2,3,4,5-tetrachloro-pheno
1,2,3,4-TETRACHLORO-6-HYDROXYBENZENE
Phenol, 2,3,4,5-tetrachloro-
2,3,4,5-tetrachlorophenate
2.3.4.5-Tetrachlor-1-hydroxy-benzol
2,3,4,5-Tetrachlor-phenol
phenol,2,3,4,5-tetrachloro
EINECS 225-531-7

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
289.4±35.0 °C at 760 mmHg

[ Melting Point ]:
69-70ºC

[ Molecular Formula ]:
C6H2Cl4O

[ Molecular Weight ]:
231.891

[ Flash Point ]:
128.8±25.9 °C

[ Exact Mass ]:
229.885971

[ PSA ]:
20.23000

[ LogP ]:
4.39

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.621

[ Storage condition ]:
APPROX 4°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SM9200000
CHEMICAL NAME :
Phenol, 2,3,4,5-tetrachloro-
CAS REGISTRY NUMBER :
4901-51-3
BEILSTEIN REFERENCE NO. :
2049590
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C6-H2-Cl4-O
MOLECULAR WEIGHT :
231.88
WISWESSER LINE NOTATION :
QR BG CG DG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
97 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - gerbil
DOSE/DURATION :
533 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
60 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,175,1990

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310 + P330-P308 + P311-P403 + P233

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T,N,Xn,F

[ Risk Phrases ]:
23/24/25-39/23/24/25-67-65-50/53-38-11-41-37/38-25

[ Safety Phrases ]:
36/37-45-62-61-60-33-29-16-36/39-26-25

[ RIDADR ]:
UN 1230 3/PG 2

[ RTECS ]:
SM9200000

Synthetic Route

Precursor & DownStream

Precursor

  • Peratox
  • 2,3,4,5-tetrachloroaniline
  • Benzene,1,2,3,4,5-pentachloro-
  • Oxetane
  • Tetrachlor-1,2-benzochinondiazid
  • Tecnazene
  • 2,3,5,6-TETRACHLOROANILINE
  • Perchlor-4,5-dihydro-phthalsaeure-anhydrid
  • nonachloropredioxin

DownStream

  • Peratox
  • 2,3,5-Trichlorophenol
  • Dibenzo[b,d]furan
  • 4-chlorodibenzofuran

Articles

Acute dermal toxicity of tetrachlorophenols in the rat.

Bull. Environ. Contam. Toxicol. 31(6) , 680-5, (1983)

Degradation of pentachlorophenol with the presence of fermentable and non-fermentable co-substrates in a microbial fuel cell.

Bioresour. Technol. 102(19) , 8762-8, (2011)

Pentachlorophenol (PCP) was more rapidly degraded in acetate and glucose-fed microbial fuel cells (MFCs) than in open circuit controls, with removal rates of 0.12 ± 0.01 mg/Lh (14.8 ± 1.0 mg/g-VSS-h) ...


More Articles


Related Compounds

  • 2,3,4,5-tetrachlorophenol anisole
  • 2,3,4,5-tetrachlorophenol acetate
  • 2,3,4,5-tetrachlorophenol anisole
  • sodium,2,3,4,5-tetrachlorophenolate
  • potassium salt of 2,3,4,5-tetrachlorophenol
  • 2-(3,4,5-Trimethoxyphenyl)-2,3-dihydro-4H-benzo[h]chromen-4-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine