(S)-Nornicotine
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Names
[ CAS No. ]:
494-97-3
[ Name ]:
(S)-Nornicotine
[Synonym ]:
(S)-3-(Pyrrolidin-2-yl)pyridine
3-(2-Pyrrolidinyl)pyridine
3-(2S)-2-pyrrolidinylpyridine
(S)-Nornicotine
3-[(2S)-pyrrolidin-2-yl]pyridine
Chemical & Physical Properties
[ Density]:
1.043g/cm3
[ Boiling Point ]:
269.999ºC at 760 mmHg
[ Molecular Formula ]:
C9H12N2
[ Molecular Weight ]:
148.20500
[ Flash Point ]:
111.291ºC
[ Exact Mass ]:
148.10000
[ PSA ]:
24.92000
[ LogP ]:
1.83490
[ Vapour Pressure ]:
0.007mmHg at 25°C
[ Index of Refraction ]:
1.536
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QS6405000
- CHEMICAL NAME :
- Nicotine, 1'-demethyl-, (S)-
- CAS REGISTRY NUMBER :
- 494-97-3
- BEILSTEIN REFERENCE NO. :
- 0081968
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C9-H12-N2
- MOLECULAR WEIGHT :
- 148.23
- WISWESSER LINE NOTATION :
- T6NJ C- BT5MTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 23500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14660 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3409 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >13700 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 2500 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 124,281,1983
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%