guvacoline

Names

[ CAS No. ]:
495-19-2

[ Name ]:
guvacoline

[Synonym ]:
Norarecoline
methyl 1,2,3,6-tetrahydropyridine-5-carboxylate
methyl 1,2,5,6-tetrahydropyridine-3-carboxylate
Guvacoline
guvacine methyl ester
5-methoxycarbonyl-1,2,3,6-tetrahydropyridine
methyl 1,2,5,6-tetrahydro-3-pyridinecarboxylate
3-Methoxycarbonyl-1,2,5,6-tetrahydropyridine

Chemical & Physical Properties

[ Density]:
1.074g/cm3

[ Boiling Point ]:
209.1ºC at 760mmHg

[ Melting Point ]:
144ºC

[ Molecular Formula ]:
C₇H₁₂BrNO₂

[ Molecular Weight ]:
222.08000

[ Flash Point ]:
80.2ºC

[ Exact Mass ]:
221.00500

[ PSA ]:
38.33000

[ LogP ]:
1.36600

[ Vapour Pressure ]:
0.207mmHg at 25°C

[ Index of Refraction ]:
1.474

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Guvacine
5-epi-Isofagomine
1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid
Tiagabine
(R)-Boc-Nipecotic acid
1-TERT-BUTYL 3-METHYL 2,3-DIHYDROPYRIDINE-1,3(6H)-DICARBOXYLATE
methyl 1-azabicyclo[2.2.2]octane-3-carboxylate