Isoindoline

Suppliers

Names

[ CAS No. ]:
496-12-8

[ Name ]:
Isoindoline

[Synonym ]:
MFCD00605324
1,2-dihydroisoindole
1H-Isoindole, 2,3-dihydro-
2,3-Dihydro-1H-isoindole
1,3-Dihydro-2H-isoindole
Isoindoline
DIHYDROISOINDOLE
1,3-dihydro-isoindol
1,3-Dihydroisoindole
o-Xyleneimine
2,3-dihydroisoindole
1H-Isoindole,2,3-dihydro

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
199.6±9.0 °C at 760 mmHg

[ Melting Point ]:
17ºC

[ Molecular Formula ]:
C8H9N

[ Molecular Weight ]:
119.164

[ Flash Point ]:
75.8±14.2 °C

[ Exact Mass ]:
119.073502

[ PSA ]:
12.03000

[ LogP ]:
1.01

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.562

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

  • 2-BENZYLISOINDOLINE
  • Phthalonitrile
  • 2-(4-methylphenyl)sulfonyl-1,3-dihydroisoindole
  • α,α′-dibromo-o-xylene
  • o-Xylylene dichloride
  • 1H-isoindole
  • 2-Methylquinolin-8-amine
  • 1-[cyano-N-4-chlorophenylcarbamylmethylene]-3-iminoisoindoline
  • (2-(Aminomethyl)phenyl)methanol

DownStream

  • Isoindolin-5-amine hydrochloride
  • 5-Nitroisoindoline
  • 2-Benzoyl-1,3-dihydro-2H-isoindole
  • N-Boc-5-aminoisoindoline
  • 5-Amino-1,3-dihydroisoindole-2-carboxylic acid tert-butyl ester
  • 11H-isoindolo[2,1-a]benzimidazole
  • 2-(2-methylbut-3-yn-2-yl)-1,3-dihydroisoindole
  • 2,3-DIHYDRO-1H-ISOINDOLE-2-ETHANOL
  • ethyl 1,3-dihydroisoindole-2-carboxylate

Articles

The EpiOcular Eye Irritation Test (EIT) for hazard identification and labelling of eye irritating chemicals: protocol optimisation for solid materials and the results after extended shipment.

Altern. Lab. Anim. 43 , 101-27, (2015)

The 7th Amendment to the EU Cosmetics Directive and the EU REACH Regulation have reinforced the need for in vitro ocular test methods. Validated in vitro ocular toxicity tests that can predict the hum...

Isoindoline Derivatives of α-Amino Acids as Cyclooxygenase 1 and 2 Inhibitors.

Arch. Pharm. (Weinheim) 349 , 175-85, (2016)

IC50 values were obtained for two series of isoindolines derived from α-amino acids over cyclooxygenase 1 and 2 (COX-1 and COX-2). In order to explain the biological activity observed, a structure-act...

Organic Synth. 83 , 70, (2006)


More Articles


Related Compounds

  • isoindoline
  • isoindoline
  • ISOINDOLINE HCL
  • ISOINDOLINE HCL
  • N-Boc-isoindoline
  • diaminoisoindoline