NORCAMPHOR

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Names

[ CAS No. ]:
497-38-1

[ Name ]:
NORCAMPHOR

[Synonym ]:
Bicyclo[2.2.1]heptan-2-one
Norbornan-2-one
Norbornanone
Bicyclo[2.2.1]-2-heptanone
2-Norbornanone
EINECS 207-846-1
2-Norcamphor
MFCD00074823
2-oxonorbornane
Norcampher
NORCAMPHOR
3-norbornanone
NorcaMphor 5GR

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
170.0±0.0 °C at 760 mmHg

[ Melting Point ]:
93-96 °C(lit.)

[ Molecular Formula ]:
C7H10O

[ Molecular Weight ]:
110.154

[ Flash Point ]:
33.9±0.0 °C

[ Exact Mass ]:
110.073166

[ PSA ]:
17.07000

[ LogP ]:
0.62

[ Vapour Pressure ]:
1.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.511

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RB7680000
CHEMICAL NAME :
2-Norbornanone
CAS REGISTRY NUMBER :
497-38-1
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H10-O
MOLECULAR WEIGHT :
110.17
WISWESSER LINE NOTATION :
L55 A CVTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04039

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
F:Highlyflammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16-S33

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
RB7680000

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

Synthetic Route

Click to get detail synthetic route

Articles

Conformational landscape and the selectivity of cytochrome P450cam.

J. Phys. Chem. B 119 , 6620-7, (2015)

Conformational heterogeneity and dynamics likely contribute to the remarkable activity of enzymes but are challenging to characterize experimentally. These features are of particular interest within t...

Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam.

Biochemistry 41(49) , 14499-508, (2002)

The role of protein structural flexibility and substrate dynamics in catalysis by cytochrome P450 enzymes is an area of current interest. We have addressed these in cytochrome P450(cam) (P450(cam)) an...

Conformational relaxation in hemoproteins: the cytochrome P-450cam case.

Biochemistry 39(46) , 14219-31, (2000)

Photodissociation of (CO)P-450(cam)(substrate) complexes was found to trigger a conformational relaxation process that interferes with ligand rebinding at temperatures as low as 140 K even though the ...


More Articles

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