g418
Names
[ CAS No. ]:
49863-47-0
[ Name ]:
g418
[Synonym ]:
Gentamicin G-418
Gentamycin B
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
Betamicina [INN-Spanish]
Gentamicin B
Betamicina
BETAMICIN
Betamicinum [INN-Latin]
Betamicine [INN-French]
Betamicin [INN]
Chemical & Physical Properties
[ Density]:
1.47 g/cm3
[ Boiling Point ]:
760.3ºC at 760 mmHg
[ Molecular Formula ]:
C20H40N4O10
[ Molecular Weight ]:
496.55200
[ Flash Point ]:
413.6ºC
[ Exact Mass ]:
496.27400
[ PSA ]:
248.39000
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
H2O: 50 mg/mL
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WK2132600
- CHEMICAL NAME :
- D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-alpha-D-gluco-heptopy ranosyl-(1-4)-O- (3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyr anosyl-(1-6))-
- CAS REGISTRY NUMBER :
- 49863-47-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H40-N4-O10
- MOLECULAR WEIGHT :
- 496.64
- WISWESSER LINE NOTATION :
- T6OTJ CZ DQ EQ FYQ1 BO- BL6TJ AZ CQ EZ DO- BT6OTJ CQ DM1 EQ E1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Fibroblast
- DOSE/DURATION :
- 75 mg/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 21,67,1993
Safety Information
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
22-24/25
[ WGK Germany ]:
3