2,3-Dichlorobenzoic acid

Suppliers

Names

[ CAS No. ]:
50-45-3

[ Name ]:
2,3-Dichlorobenzoic acid

[Synonym ]:
Benzoic acid,2,3-dichloro
2,3-Dichlorobenzoicacid
2,3-Dichlorobenzoic
QVR BG CG
RARECHEM AL BO 0323
3-Dichlorobenzoic acid
EINECS 200-039-5
2,3-dichloro-benzoicaci
2,3-dichlorbenzoic acid
2,3-DICHLOROBENZOIC ACID pure
2,3-Dichlorobenzoic Acid
2,3-Dichlor-benzoesaeure
dichlorobenzoic acid
2,3-Dichlorbenzoesure
Lamotrigine Related Compound B (USP)
MFCD00002413
Benzoic acid, 2,3-dichloro-
Lamotrigine Impurity 4

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
306.9±22.0 °C at 760 mmHg

[ Melting Point ]:
168-170 °C(lit.)

[ Molecular Formula ]:
C₇H₄Cl₂O₂

[ Molecular Weight ]:
191.012

[ Flash Point ]:
139.4±22.3 °C

[ Exact Mass ]:
189.958832

[ PSA ]:
37.30000

[ LogP ]:
2.92

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.599

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG6475000

CHEMICAL NAME :: Benzoic acid, 2,3-dichloro-

CAS REGISTRY NUMBER :: 50-45-3

BEILSTEIN REFERENCE NO. :: 1946217

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H4-Cl2-O2

MOLECULAR WEIGHT :: 191.01

WISWESSER LINE NOTATION :: QVR BG CG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 13,1538,1964

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
DG6475000

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DICHLOROTOLUENE
benzonitrile, dichloro-
2,3-Dichlorobenzyl bromide
Carbon dioxide
1,2-Dichlorobenzene
2,3-Dichlorobenzoic acid sodium salt
2,3-dichlorobenzamide
1,2,3-trichlorobenzene
1,4-Dichlorobenzene
2,3-Dichloroaniline

DownStream

2,3-DICHLOROBENZYL ALCOHOL
N-[4-[(6-chloro-[1,3]dioxolo[4,5-b]acridin-10-yl)amino]-3-methoxyphenyl]methanesulfonamide
3-chloro-2-(p-tolyloxy)benzoic acid
3-Chlorobenzoic Acid
2,3-Dichlorobenzoyl
2,3-Dichlorobenzoyl cyanide
1,2-Dichlorobenzene
2,3-dichlorobenzamide
benzonitrile, dichloro-
2-Amino-3-chlorobenzoic acid

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

A Novel Transformation of Polychlorinated Biphenyls by Rhodococcus sp. Strain RHA1.

Appl. Environ. Microbiol. 61(9) , 3353-8, (1995)

We have characterized a biphenyl degrader, Rhodococcus sp. strain RHA1. Biphenyl-grown cells of strain RHA1 efficiently transformed 45 components in the 62 major peaks of a polychlorinated biphenyl (P...

New advances in plant growth-promoting rhizobacteria for bioremediation.

Environ. Int. 33(3) , 406-13, (2007)

Plant growth-promoting rhizobacteria (PGPR) are bacteria capable of promoting plant growth by colonizing the plant root. For a long period PGPR were mainly used for assisting plants to uptake nutrient...