[Lys8]-Vasopressin TFA
Suppliers
Names
[ CAS No. ]:
50-57-7
[ Name ]:
[Lys8]-Vasopressin TFA
[Synonym ]:
EINECS 200-050-5
syntopressin
postacton
Lysipressin Acetate
CYFQNCPKG-NH2
LVP
[Lys8]-vasopressin
LYSPRESSIN
lypressin
8-lysine-vasopressin
lysinepitressin
diapid
lysine-vasopressin
Glycinamide, 1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-prolyl-L-lysyl-
L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide Cyclic (1®6)-Disulfide
(8-Lysine)vasopressin
1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-lysylglycinamide
Lysipressin
Lysine Vasopressin
Cys-Pro-Arg-Gly-NH2
c[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2
CYS-TYR-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2(DISULFIDE BRIDGE:CYS1-CYS6)
Lypressin Acetate
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
1610.4±65.0 °C at 760 mmHg
[ Molecular Formula ]:
C46H65N13O12S2
[ Molecular Weight ]:
1056.218
[ Flash Point ]:
927.7±34.3 °C
[ Exact Mass ]:
1055.431763
[ PSA ]:
476.15000
[ LogP ]:
-5.74
[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.581
[ Storage condition ]:
−20°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YW8659000
- CHEMICAL NAME :
- Vasopressin, 8-L-lysine-
- CAS REGISTRY NUMBER :
- 50-57-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C46-H65-N13-O12-S2
- MOLECULAR WEIGHT :
- 1056.36
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 5 iu/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - maternal-fetal exchange
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 17,419,1968
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraarterial
- DOSE :
- 0.25 iu/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - maternal-fetal exchange
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 17,419,1968
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H332
[ Precautionary Statements ]:
P261
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20
[ Safety Phrases ]:
S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
YW8659000
Precursor & DownStream
Precursor
DownStream
Articles
PLoS ONE 8(1) , e52683, (2013)
Only a limited proportion of patients needing pharmacological control of portal hypertension are hemodynamic responders to propranolol. Here we analyzed the effects of zolmitriptan on portal pressure ...
J. Surg. Res. 188(2) , 503-9, (2014)
Background Septic shock is still related to unacceptably high morbidity and mortality. Microcirculatory alteration has been demonstrated to be one important reason associated with this evolution. Vaso...
J. Int. Med. Res. 40(5) , 1735-44, (2012)
To investigate the presence of aquaporin (AQP) 1 and AQP2 in kidneys of cirrhotic rats with ascites, and to determine the effect of terlipressin on AQP1 and AQP2 levels and its therapeutic efficacy in...