2,3,5-Trichlorobenzoic acid

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Names

[ CAS No. ]:
50-73-7

[ Name ]:
2,3,5-Trichlorobenzoic acid

[Synonym ]:
RARECHEM AL BE 0200
EINECS 210-380-1
Benzoic acid, 2,3,5-trichloro-
2,3,5-Trichlorobenzoic
2,3,5-TRICHLOROBENZOIC ACID PESTANAL100
MFCD00060674
2,3,5-Trichlorobenzoic acid
2,3,5-TBA
2,3,5-trichloro-benzoicaci
2,3,4,6-TETRA-O-ACETYL-B-D-GLUCOPYRANOSYL ETHYLXANTHATE
2,3,5-Trichlor-benzoesaeure
2,3,5,-Trichlorobenzoic acid

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
329.4±37.0 °C at 760 mmHg

[ Melting Point ]:
166-167 °C(lit.)

[ Molecular Formula ]:
C7H3Cl3O2

[ Molecular Weight ]:
225.456

[ Flash Point ]:
153.0±26.5 °C

[ Exact Mass ]:
223.919861

[ PSA ]:
37.30000

[ LogP ]:
3.87

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.611

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH7525000
CHEMICAL NAME :
Benzoic acid, 2,3,5-trichloro-
CAS REGISTRY NUMBER :
50-73-7
BEILSTEIN REFERENCE NO. :
2097064
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H3-Cl3-O2
MOLECULAR WEIGHT :
225.45
WISWESSER LINE NOTATION :
QVR BG CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 13,1538,1964

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DH7525000

[ HS Code ]:
2916399090

Precursor & DownStream

Precursor

  • Sulfuric acid
  • chloramben
  • 2,3,5-Trichlorobenzaldehyde
  • 2-Amino-3,5-dichlorobenzoic acid
  • 1,2,5-Trichloro-3-methylbenzene
  • Acetophenone
  • 2,3,5-trichlorobenzonitrile
  • 2,5-Dichlorobenzaldehdye
  • 2,5-dichloro-3-nitro-benzaldehyde

DownStream

  • (2,3,5-Trichlorophenyl)methanol

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.

J. Med. Chem. 52 , 6931-5, (2009)

We show that phenoxyauxin herbicides and lipid-lowering fibrates inhibit human but not rodent T1R3. T1R3 as a coreceptor in taste cells responds to sweet compounds and amino acids; in endocrine cells ...

Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines bearing trichlorophenyl moiety.

Eur. J. Med. Chem. 43 , 808-15, (2008)

The reaction of 2,3,5-trichlorobenzoic acid hydrazide with carbon disulfide and potassium hydroxide followed by treatment with hydrazine hydrate afforded 3-(2,3,5-trichlorophenyl)-4-amino-1,2,4-triazo...

Rearrangement of Halotropones. Chloride Exchange in Tribromotropolone. Doering WE and Knox LH.

J. Am. Chem. Soc. 74(22) , 5683-87, (1952)


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Related Compounds

  • tricamba
  • 2,3,5-trihydroxypentanoic acid
  • 2,3,4-Trichloro-5-fluorobenzoic acid
  • 2,3,5,6-tetrabromobenzoic acid
  • 2-(3,5-dichlorophenyl)propanedioic acid
  • 2-(3,5-dichloroanilino)butanedioic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • Ethyl 5-aminothieno[2,3-c]pyridazine-6-carboxylate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 5-[(N-methylacetamido)methyl]furan-2-carboxylic acid
  • 4-(1-Amino-3-hydroxypropan-2-yl)-2-ethoxyphenol
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde