5-Chloro-2'-deoxyuridine

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Names

[ CAS No. ]:
50-90-8

[ Name ]:
5-Chloro-2'-deoxyuridine

[Synonym ]:
5-CHLORODEOXYURIDINE
MFCD00006531
5-CHLORODESOXYURIDINE
5-Chloro-2'-deoxy-D-uridine
CLUDR
5-Chlorodeoxyuridin
CldU
2'-DEOXY-5-CHLOROURIDINE
Chlorodeoxyuridine

Chemical & Physical Properties

[ Density]:
1.67 g/cm3

[ Melting Point ]:
176-179ºC

[ Molecular Formula ]:
C9H11ClN2O5

[ Molecular Weight ]:
262.64700

[ Exact Mass ]:
262.03600

[ PSA ]:
104.55000

[ Index of Refraction ]:
1.644

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU7400000
CHEMICAL NAME :
Uridine, 5-chloro-2'-deoxy-
CAS REGISTRY NUMBER :
50-90-8
LAST UPDATED :
199709
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C9-H11-Cl-N2-O5
MOLECULAR WEIGHT :
262.67
WISWESSER LINE NOTATION :
T6NVMVJ EG A- ET5OTJ B1Q CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
500 nmol/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,301,1982 *** REVIEWS *** TOXICOLOGY REVIEW 32XPAD "Teratology," Berry, C.L., and D.E. Poswillo, eds., New York, Springer, 1975 Volume(issue)/page/year: -,49,1975

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332-H351

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
36/37/39-45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YU7400000

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • [(2R,3S,5R)-3-acetyloxy-5-(5-chloro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
  • 2'-deoxyuridine
  • 3,5'-Di-O-acetyl-2'-deoxyuridine
  • idoxuridine
  • 5-Chlorouracil
  • Thymidine

DownStream

  • 5-Chlorouracil

Customs

[ HS Code ]: 2942000000

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Related Compounds

  • 3'-epi-5-Chloro-2'-deoxyuridine
  • 4'-Azido-5-chloro-2'-deoxyuridine
  • 5-chloro-2'-deoxyuridine 5'-triphosphate
  • 5-Chloro-2'-deoxyuridine 3',5'-Diacetate
  • 5-chloro-5-ethyl-6-methoxy-5,6-dihydro-2'-deoxyuridine
  • 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine
  • N-[1-(pyridin-2-yl)azetidin-3-yl]-2-[4-(trifluoromethyl)phenyl]acetamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4-{6-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyridazin-3-yl}morpholine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • [(2Z)-3-(acetylcarbamoyl)-6-chloro-2H-chromen-2-ylidene]amino acetate
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde