Benorilate
Suppliers
Names
[ CAS No. ]:
5003-48-5
[ Name ]:
Benorilate
[Synonym ]:
Fenasprate
4'-(Acetamido)phenyl-2-acetoxybenzoate
Fenasparate
(1E)-N-{4-[(2-Acetoxybenzoyl)oxy]phenyl}ethanimidic acid
4-Acetamidophenyl 2-acetoxybenzoate
p-Acetamidophenyl acetylsalicylate
Benzoic acid, 2-(acetyloxy)-, 4-[[(1E)-1-hydroxyethylidene]amino]phenyl ester
Benorilate
EINECS 225-674-5
4-(acetylamino)phenyl 2-(acetyloxy)benzoate
Benorylate
MFCD00864257
Aspirin acetaminophen ester
(4-acetamidophenyl) 2-acetyloxybenzoate
Benzoic acid, 2-(acetyloxy)-, 4-(acetylamino)phenyl ester
Salicylic Acid Acetate Ester with 4-Hydroxyacetanilide
4-Acetamidophenyl salicylate acetate
Salipran
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
511.5±60.0 °C at 760 mmHg
[ Melting Point ]:
177-181ºC
[ Molecular Formula ]:
C17H15NO5
[ Molecular Weight ]:
313.305
[ Flash Point ]:
263.1±32.9 °C
[ Exact Mass ]:
313.095032
[ PSA ]:
81.70000
[ LogP ]:
2.22
[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C
[ Index of Refraction ]:
1.566
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VO0720000
- CHEMICAL NAME :
- Salicylic acid, acetate, ester with 4'-hydroxyacetanilide
- CAS REGISTRY NUMBER :
- 5003-48-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C17-H15-N-O5
- MOLECULAR WEIGHT :
- 313.33
- WISWESSER LINE NOTATION :
- 1VOR BVOR DMV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 1280 mg/kg/8D-I
- TOXIC EFFECTS :
- Behavioral - hallucinations, distorted perceptions Lungs, Thorax, or Respiration - respiratory stimulation Nutritional and Gross Metabolic - dehydration
- REFERENCE :
- BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 288,1344,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0080609
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1830 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3431293
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1551 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,1692,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1255 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3431293 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3960 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 20,143,1980
Safety Information
[ Hazard Codes ]:
Xi
[ HS Code ]:
2924299090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%