Beclamide

Names

[ CAS No. ]:
501-68-8

[ Name ]:
Beclamide

[Synonym ]:
Hibicon
3-Chlor-propionsaeure-benzylamid
Neuracen
3-Chlor-N-benzyl-propionamid
Chlorakon
Nidrane
Chloracon
Beclamide
3-chloro-propionic acid benzylamide
Posedrine
Beklamid
Nydran
Nydrane

Chemical & Physical Properties

[ Density]:
1.145g/cm3

[ Boiling Point ]:
386.9ºC at 760mmHg

[ Molecular Formula ]:
C10H12ClNO

[ Molecular Weight ]:
197.66100

[ Flash Point ]:
187.8ºC

[ Exact Mass ]:
197.06100

[ PSA ]:
29.10000

[ LogP ]:
2.32260

[ Index of Refraction ]:
1.532

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UE3150000
CHEMICAL NAME :
Propionamide, N-benzyl-3-chloro-
CAS REGISTRY NUMBER :
501-68-8
BEILSTEIN REFERENCE NO. :
2720702
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H12-Cl-N-O
MOLECULAR WEIGHT :
197.68
WISWESSER LINE NOTATION :
G2VM1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 107,403,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
770 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 107,403,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
770 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,384,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,99,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,384,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1368 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 28,452,1994

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Precursor

  • 3-Chloropropanoyl chloride
  • Benzylamine
  • 3-Chloropropionic Acid
  • Acrylic acid

DownStream

  • N-Benzylacrylamide
  • 1-benzylazetidin-2-one

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%