Desaminotyrosine

Suppliers

Names

[ CAS No. ]:
501-97-3

[ Name ]:
Desaminotyrosine

[Synonym ]:
Benzenepropanoic acid, 4-hydroxy-
4-hydroxy-benzenepropanoic acid
MFCD00002778
3-(p-hydroxyphenyl)propionic acid
4-Hydroxyhydrocinnamic Acid
3-(4-Hydroxyphenyl)propanoic acid
Phloretic acid
3-(p-Hydroxyphenyl)propionic acid,Phloretic acid
3-(para-Hydroxyphenyl)propionic acid
3-(4-Hydroxyphenyl)-propionic acid
3-(4-Hydroxyphenyl)propionic acid
b-(p-Hydroxyphenyl)propionic acid
p-hydroxy-hydrocinnamic acid
EINECS 207-931-3

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
352.4±17.0 °C at 760 mmHg

[ Melting Point ]:
129-131 °C(lit.)

[ Molecular Formula ]:
C₉H₁₀O₃

[ Molecular Weight ]:
166.174

[ Flash Point ]:
181.1±17.4 °C

[ Exact Mass ]:
166.062988

[ PSA ]:
57.53000

[ LogP ]:
1.10

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.580

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MW5342000

CHEMICAL NAME :: Hydrocinnamic acid, p-hydroxy-

CAS REGISTRY NUMBER :: 501-97-3

BEILSTEIN REFERENCE NO. :: 2209841

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H10-O3

MOLECULAR WEIGHT :: 166.19

WISWESSER LINE NOTATION :: QV2R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1809 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 12,265,1976

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MW5342000

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

p-Hydroxy-cinnamic acid
3-(4-((2,4-dimethylbenzyl)oxy)phenyl)propanoic acid
3-(4-Methoxyphenyl)propanoic acid
3-[4-(Benzyloxy)Phenyl]Acrylic Acid
4-hydroxybenzaldehyde
1-(4-Hydroxyphenyl)propan-1-one
3-(4-Hydroxyphenyl)propionic acid benzyl ester
3-(4-((2,4-dimethylbenzyl)oxy)phenyl)acrylic acid
Ethyl 3-(4-methoxyphenyl)propanoate
L-Tyrosine

DownStream

7-Hydroxy-2-tetralone
Phloretin
4-hydroxy-6-[2-(4-hydroxyphenyl)ethyl]pyran-2-one
3-(4-Hydroxyphenyl)propionic acid benzyl ester
cetraxate
Benzenepropanoic acid,4-hydroxy-, 2,5-dioxo-1-pyrrolidinyl ester
Benzenepropanoic acid,4-ethoxy-
Tyramine
3-(4-Benzyloxyphenyl)propionic acid
3-(4-hydroxyphenyl)propanal

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Articles

Hydroxycinnamic acids used as external acceptors of electrons: an energetic advantage for strictly heterofermentative lactic acid bacteria.

Appl. Environ. Microbiol. 80(24) , 7574-82, (2014)

The metabolism of hydroxycinnamic acids by strictly heterofermentative lactic acid bacteria (19 strains) was investigated as a potential alternative energy route. Lactobacillus curvatus PE5 was the mo...

A metabolite profiling approach to identify biomarkers of flavonoid intake in humans.

J. Nucl. Med. 139 , 2309-14, (2009)

Flavonoids are phytochemicals that are widespread in the human diet. Despite limitations in their bioavailability, experimental and epidemiological data suggest health benefits of flavonoid consumptio...

Development of a targeted method for twenty-three metabolites related to polyphenol gut microbial metabolism in biological samples, using SPE and UHPLC-ESI-MS/MS.

Talanta 128 , 221-30, (2014)

An increasing number of studies have concerned the profiling of polyphenol microbial metabolites, especially in urine or plasma, but only a few have regarded their accurate quantification. This study ...

tert-butyl N-[(1-hydroxy-3-methylcyclohexyl)methyl]-N-[(methylcarbamoyl)methyl]carbamate
tert-butyl N-(1-hydroxy-2-phenylpropan-2-yl)-N-methylcarbamate
Tert-butyl 3-(1-{[(tert-butoxy)carbonyl](methyl)amino}ethyl)-3-hydroxyazetidine-1-carboxylate
tert-butyl N-methyl-N-(1,1,1-trifluoro-3-hydroxy-2-phenylpropan-2-yl)carbamate
tert-butyl N-(4,6-dichloro-2-hydroxy-2,3-dihydro-1H-inden-1-yl)-N-methylcarbamate
tert-butyl N-[3-chloro-5-(hydroxymethyl)phenyl]-N-methylcarbamate
tert-butyl N-[2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-methylcarbamate
tert-butyl N-[5-(4-hydroxypiperidine-1-carbonyl)-1,3,4-thiadiazol-2-yl]carbamate
tert-butyl N-{4-[1-(2-hydroxyethyl)-1H-1,3-benzodiazol-2-yl]phenyl}carbamate
tert-butyl N-{4-[2-(4-hydroxypiperidin-1-yl)ethyl]phenyl}carbamate

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.