1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid

Names

[ CAS No. ]:
50264-63-6

[ Name ]:
1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid

[Synonym ]:
1H-Indazole-3-carboxylic acid,1-(p-fluorobenzyl)
1-(4-fluoro-benzyl)-1H-indazole-3-carboxylic acid
1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid
1H-Indazole-3-carboxylic acid, 1-[(4-fluorophenyl)methyl]-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
495.5±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C15H11FN2O2

[ Molecular Weight ]:
270.258

[ Flash Point ]:
253.4±24.6 °C

[ Exact Mass ]:
270.080444

[ PSA ]:
55.12000

[ LogP ]:
3.16

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.640

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NK7886400
CHEMICAL NAME :
1H-Indazole-3-carboxylic acid, 1-(p-fluorobenzyl)-
CAS REGISTRY NUMBER :
50264-63-6
BEILSTEIN REFERENCE NO. :
0888595
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H11-F-N2-O2
MOLECULAR WEIGHT :
270.28
WISWESSER LINE NOTATION :
T56 BNNJ B1R DF& DVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
377 mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 19,778,1976

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl 1-(4-fluorobenzyl)-1H-indazole-3-carboxylate
  • methyl indazolyl-3-carboxylate
  • 4-Fluorobenzyl bromide

DownStream

  • AB-FUBINACA

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 1-(4-Bromobenzyl)-1H-indazole-3-carboxylic acid
  • 1-(4-methylbenzoyl)-1H-indazole-3-carboxylic acid phenylamide
  • 1-(4-chlorobenzoyl)-1H-indazole-3-carboxylic acid phenylamide
  • 1-(4-BROMOPHENYL)-1H-INDAZOLE-3-CARBOXYLIC ACID
  • 1-(4-fluorobenzoyl)-1H-indazole-3-carboxylic acid phenylamide
  • 1-(4-Chlorobenzyl)-5-nitro-1H-indazole-3-carboxylic acid