O-Desmethyl apixaban

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Names

[ CAS No. ]:
503612-76-8

[ Name ]:
O-Desmethyl apixaban

[Synonym ]:
4-Demethoxy-4-hydroxy Apixaban
O-demethyl-apixaban
Apixaban Impurity 18

Chemical & Physical Properties

[ Molecular Formula ]:
C24H23N5O4

[ Molecular Weight ]:
445.47100

[ Exact Mass ]:
445.17500

[ PSA ]:
122.75000

[ LogP ]:
3.41080

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1(2H)-pyridinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

DownStream

Related Compounds

  • O-desmethyl Mebeverine acid
  • (4R)-4-(ethylamino)-2-(3-hydroxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide-1,1-dioxide
  • O-Desmethyl Midostaurin
  • O-Desmethyl gefitinib
  • O-Desmethyl Quinidine
  • O-Desmethyl Felodipine
  • Azepane-1-carboximidamide hydrochloride
  • Methyl 2-[(6-methyl-3-pyridinyl)oxy]benzeneacetate
  • N-(3-(dimethylamino)propyl)-N-(6-ethylbenzo[d]thiazol-2-yl)-3-(phenylsulfonyl)propanamide hydrochloride
  • 2-amino-N-benzyl-N-ethylbutanamide
  • 5-Amino-2-methoxy-4-(methylthio)phenol
  • methyl[(2S)-2-(pyrrolidin-1-yl)propyl]amine
  • 2-chloro-N-((1-(3,4-dimethylphenyl)-1H-tetrazol-5-yl)methyl)-5-nitrobenzamide
  • ((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl octyl hydrogen phosphate
  • 3-Hydroxy-Alpha-methyl-tyrosine Methyl Ester
  • 2-Chloro-3-fluoro-6-nitrophenol
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