O-Desmethyl apixaban

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Names

[ CAS No. ]:
503612-76-8

[ Name ]:
O-Desmethyl apixaban

[Synonym ]:
4-Demethoxy-4-hydroxy Apixaban
O-demethyl-apixaban
Apixaban Impurity 18

Chemical & Physical Properties

[ Molecular Formula ]:
C24H23N5O4

[ Molecular Weight ]:
445.47100

[ Exact Mass ]:
445.17500

[ PSA ]:
122.75000

[ LogP ]:
3.41080

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1(2H)-pyridinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

DownStream

Related Compounds

  • O-desmethyl Mebeverine acid
  • (4R)-4-(ethylamino)-2-(3-hydroxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide-1,1-dioxide
  • O-Desmethyl Midostaurin
  • O-Desmethyl gefitinib
  • O-Desmethyl Quinidine
  • O-Desmethyl Felodipine
  • tert-butyl 2-(aminomethyl)-7,8-dihydro-4H-pyrazolo[1,5-a][1,4]diazepine-5(6H)-carboxylate
  • PentaFluoroSulfide PerFluorooctanoic Acid
  • 2-[[4-Fluoro-6-[methyl[2-[[2-(sulfooxy)ethyl]sulfonyl]ethyl]amino]-1,3,5-triazin-2-yl]amino]-5-hydroxy-6-[2-(4-methyl-2-sulfophenyl)diazenyl]-1,7-naphthalenedisulfonic acid sodium salt (1:4)
  • 2-Chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)phenol
  • 2-Chloro-1-methoxy-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzene
  • 4-[2-hydroxy-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butoxyl)-benzoic acid
  • Hexythiazox metabolite PT-1-5
  • hexasodium;32-[[3-[[3-methyl-5-oxo-1-[2-sulfo-4-[(Z)-2-[2-sulfo-3-[(2,5,6-trichloropyrimidin-4-yl)amino]phenyl]ethenyl]phenyl]-4H-pyrazol-4-yl]diazenyl]-4-sulfophenyl]sulfamoyl]-2,11,20,29,37,39-hexaza-38,40-diazanidanonacyclo[28.6.1.13,10.112,19.121,28.04,9.013,18.022,27.031,36]tetraconta-2,4(9),5,7,10,12(39),13(18),14,16,20,22(27),23,25,28,30(37),31(36),32,34-octadecaene-5,14,23-trisulfonic acid;nickel
  • n:2 FTSAAAm n=6
  • 1-Hydroxy-5:2 fluorotelomer sulfonate
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