O-Desmethyl apixaban

Suppliers

Names

[ CAS No. ]:
503612-76-8

[ Name ]:
O-Desmethyl apixaban

[Synonym ]:
4-Demethoxy-4-hydroxy Apixaban
O-demethyl-apixaban
Apixaban Impurity 18

Chemical & Physical Properties

[ Molecular Formula ]:
C24H23N5O4

[ Molecular Weight ]:
445.47100

[ Exact Mass ]:
445.17500

[ PSA ]:
122.75000

[ LogP ]:
3.41080

Synthetic Route

Precursor & DownStream

Precursor

  • ethyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1(2H)-pyridinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

DownStream


Related Compounds

  • O-desmethyl Mebeverine acid
  • (4R)-4-(ethylamino)-2-(3-hydroxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide-1,1-dioxide
  • O-Desmethyl Midostaurin
  • O-Desmethyl gefitinib
  • O-Desmethyl Quinidine
  • O-Desmethyl Felodipine
  • (4-methyl-4H-1,2,4-triazol-3-yl)methyl 4-methylbenzene-1-sulfonate
  • (2R,3S)-3-(benzyloxy)-2-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]pentanamido}butanoic acid
  • (3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-dimethylpentanoic acid
  • (2R,3S)-3-(benzyloxy)-2-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]pentanamido}butanoic acid
  • 1-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]pentanoyl}-3-methylpiperidine-2-carboxylic acid
  • 3-cyclopropyl-2-({2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}formamido)propanoic acid
  • 3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2,6-difluorobenzoic acid
  • (3R)-7-bromo-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  • (3S)-3-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-difluoropropanamido]methyl}-5-methylhexanoic acid
  • 3-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylheptanamido]-2,2-difluoropropanoic acid
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