Dehydronitroso Nifedipine

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Names

[ Name ]:
Dehydronitroso Nifedipine

[Synonym ]:
Dehydronitroso Nifedipine
dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate
Nifedipine Nitrosophenylpyridine Analog
Nifedipine impurity B
Dehydronitrosonifedipine
4-(2-Nitrosophenyl)-2,6-dimethyl-3,5-dimethoxycarbonylpyridine
Nifedipine Impurity 2

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
449ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₆N₂O₅

[ Molecular Weight ]:
328.31900

[ Flash Point ]:
225.3ºC

[ Exact Mass ]:
328.10600

[ PSA ]:
94.92000

[ LogP ]:
3.33650

[ Index of Refraction ]:
1.579

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Nifedipine
2-Nitrobenzaldehyde
Methyl acetoacetate
Methyl (Z)-3-aminocrotonate

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Spin-trapping and antioxidant properties of illuminated and nonilluminated nifedipine and nimodipine in heart homogenate and model system.

Mol. Pharmacol. 40(3) , 435-9, (1991)

Nifedipine [1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic+ ++ acid dimethyl ester] and nimodipine [1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic+ ++ acid 2-...

Determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine by derivative UV-spectrophotometry in bulk material and pharmaceutical forms.

Il Farmaco 45(6 Suppl) , 751-5, (1990)

A method for the determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine (bulk material and pharmaceutical formulations) by second-derivative ultra...

NTP, the photoproduct of nifedipine, activates caffeine-sensitive ion channels in leech neurons.

Cell Calcium 33(3) , 207-21, (2003)

Leech P neurons possess caffeine-sensitive ion channels in intracellular Ca(2+) stores and in the plasma membrane. The following results indicate that these channels are also activated by 2,6-dimethyl...

Dehydro Nifedipine-d6
Dehydro Nifedipine N-Oxide
Hydroxydehydro Nifedipine Carboxylate
M-nifedipine
Hydroxy Dehydro Nifedipine Lactone
Dehydronifedipine
4-[[(5-Chloro-2-methylphenyl)(phenylsulfonyl)amino]methyl]benzoic acid 2-[(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]hydrazide
4-[[(Methylsulfonyl)phenylamino]methyl]benzoic acid 2-[[2,5-dimethyl-1-(3-methylphenyl)-1H-pyrrol-3-yl]methylene]hydrazide
4-[[(Methylsulfonyl)phenylamino]methyl]benzoic acid 2-[[2,5-dimethyl-1-(4-methylphenyl)-1H-pyrrol-3-yl]methylene]hydrazide
4-[[(Methylsulfonyl)phenylamino]methyl]benzoic acid 2-[[1-(3,5-dimethylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]hydrazide
4-[[(3,4-Dimethylphenyl)(methylsulfonyl)amino]methyl]benzoic acid 2-[(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]hydrazide
2-[(Phenylmethyl)(phenylsulfonyl)amino]benzoic acid 2-[[2,5-dimethyl-1-(2-methylphenyl)-1H-pyrrol-3-yl]methylene]hydrazide
2-[(Phenylmethyl)(phenylsulfonyl)amino]benzoic acid 2-[[1-(3,4-dimethylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]hydrazide
2-[(Phenylmethyl)(phenylsulfonyl)amino]benzoic acid 2-[[1-(3,5-dimethylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]hydrazide
2-[(Phenylmethyl)(phenylsulfonyl)amino]benzoic acid 2-[[1-(2,6-dimethylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]hydrazide
4-Quinolineacetic acid, 8-bromo-1,2-dihydro-5-hydroxy-2-oxo-, methyl ester

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